Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.34 |
| ▸ | LCAT | P04180 | 2/20 | 0.33 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.33 |
| ▸ | SCN2B | O60939 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN1B | Q07699 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5109564 | 0.90 | NR1H2 (0.41) | NR1H2NR1H3CYP11B2CYP11B1ACACB | |
| Hydrochloric Acid SCHEMBL5123566 | 0.89 | NR1H2 (0.41) | NR1H2NR1H3CYP11B2CYP11B1ACACB | |
| SCHEMBL5108498 | 0.88 | NR1H2 (0.40) | NR1H2NR1H3CYP11B2CYP11B1ACACB | |
| SCHEMBL5107911 | 0.84 | NR1H2 (0.39) | NR1H2NR1H3CYP11B2CYP11B1CHRNB4 | |
| SCHEMBL5115900 | 0.84 | CHRNB4 (0.42) | NR1H2NR1H3CYP11B2CYP11B1CHRNB4 | |
| SCHEMBL5107359 | 0.82 | NR1H2 (0.38) | NR1H2NR1H3CYP11B2CYP11B1CHRNB4 | |
| SCHEMBL5120701 | 0.81 | CYP11B2 (0.45) | CYP11B2CYP11B1CHRNB4CHRNA3HTR2A | |
| SCHEMBL5107879 | 0.76 | CHRNB2 (0.54) | CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL5114036 | 0.75 | NR3C1 (0.38) | CYP11B2CYP11B1CHRNB4CHRNA3SCN9A | |
| Hydrochloric Acid SCHEMBL5111544 | 0.74 | CHRNB4 (0.41) | CYP11B2CYP11B1CHRNB4CHRNA3CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040106603-A1 | Diazabicyclic compounds useful in the treatment of CNS and other disorders | PFIZER INC | 2004-06-03 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106603-A1 | Diazabicyclic compounds useful in the treatment of CNS and other disorders | DBH, CHRNA6, DDT | NR1H2 513/4885NR1H3 631/4885CYP11B2 403/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.