SCHEMBL6572962

SCHEMBL6572962

Cc1ccc(NC(=O)CCl)c(O)c1

nearest known ligand 0.73

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.73
HTT P42858 1/20 0.73
SMN1; SMN2 Q16637 1/20 0.73
KMT2A Q03164 6/20 0.56
MEN1 O00255 4/20 0.56
CXCR2 P25025 1/20 0.54
GAA P10253 5/20 0.53
NPC1 O15118 3/20 0.53
RAB9A P51151 2/20 0.53
LMNA P02545 1/20 0.48
KDM4E B2RXH2 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7269751 0.86 HTT (0.68) ALDH1A1HTTSMN1; SMN2KMT2AMEN1
SCHEMBL6836552 0.84 KMT2A (0.61) ALDH1A1HTTSMN1; SMN2KMT2AMEN1
SCHEMBL6838424 0.84 LMNA (0.56) ALDH1A1HTTSMN1; SMN2KMT2AMEN1
SCHEMBL29643255 0.84 SMN1; SMN2 (1.00) ALDH1A1HTTSMN1; SMN2KMT2AMEN1
SCHEMBL4228749 0.84 SMN1; SMN2 (1.00) ALDH1A1HTTSMN1; SMN2KMT2AMEN1
SCHEMBL6836390 0.84 NPC1 (0.62) ALDH1A1HTTSMN1; SMN2KMT2AMEN1
SCHEMBL7764411 0.83 KMT2A (0.54) ALDH1A1HTTSMN1; SMN2KMT2AMEN1
SCHEMBL7264600 0.83 ALDH1A1 (0.73) ALDH1A1HTTSMN1; SMN2KMT2AMEN1
SCHEMBL2748272 0.82 ALDH1A1 (0.53) ALDH1A1HTTSMN1; SMN2KMT2AMEN1
SCHEMBL28515684 0.81 KMT2A (0.57) ALDH1A1HTTSMN1; SMN2KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6752839-B1 2-SUBSTITUTED 5-AMINOALKYLPHENOL DERIVATIVE COUPLER AND PYRAZOLES, CERTAIN PYRIMIDINES AND/OR PYRAZOLOPYRIMIDINES BASES; CHROMATIC, STRONG, AESTHETIC COLORATIONS IN VARIETY OF SHADES L'OREAL (FR) 2004-06-22 US claimed
US-6530960-B1 Oxidative base at least one 2-substituted 5-aminoalkylphenol coupler; chromatic, strong, aesthetic colorations in a variety of shades L'OREAL S.A. (FR) 2003-03-11 US claimed
EP-1093788-A1 Oxydative dyeing composition for keratinic fibres and dyeing process using this composition L'OREAL (FR) 2001-04-25 EP claimed
EP-1093790-A2 Oxydative dyeing composition for keratinic fibres and dyeing process using this composition L'OREAL (FR) 2001-04-25 EP claimed
EP-1093789-A1 Composition for oxidative dyeing of keratinous fibres and dyeing process using the same L'OREAL (FR) 2001-04-25 EP claimed
EP-1093791-A1 Composition for oxidative dyeing of keratinous fibres and dyeing process using same L'OREAL (FR) 2001-04-25 EP claimed
EP-1093793-A2 Composition for oxidative dyeing of keratinous fibres and dyeing process using same L'OREAL (FR) 2001-04-25 EP claimed
EP-1093792-A1 Composition for oxidative dyeing of keratinous fibres and dyeing process using the same L'OREAL (FR) 2001-04-25 EP claimed
US-11230680-B2 Methods for preparing fuel additives BP OIL INTERNATIONAL LIMITED (GB) 2022-01-25 US disclosed
US-11230680-B2 Methods for preparing fuel additives BP OIL INTERNATIONAL LIMITED (GB) 2022-01-25 US disclosed
CN-111936474-A Method for preparing fuel additive 英国石油国际有限公司 2020-11-13 CN disclosed
EP-3732171-A1 METHODS FOR PREPARING FUEL ADDITIVES BP Oil International Limited (GB) 2020-11-04 EP disclosed
US-20200332208-A1 Methods for Preparing Fuel Additives BP OIL INTERNATIONAL LIMITED (GB) 2020-10-22 US disclosed
US-20200332208-A1 Methods for Preparing Fuel Additives BP OIL INTERNATIONAL LIMITED (GB) 2020-10-22 US disclosed
EP-1093788-A1 Oxydative dyeing composition for keratinic fibres and dyeing process using this composition L'OREAL (FR) 2001-04-25 EP disclosed
EP-1093790-A2 Oxydative dyeing composition for keratinic fibres and dyeing process using this composition L'OREAL (FR) 2001-04-25 EP disclosed
EP-1066263-A1 NOVEL CATIONIC 2-ACYLAMINOPHENOLS, THEIR USE AS COUPLER FOR OXIDATION DYEING, COMPOSITIONS CONTAINING THEM, AND DYEING METHODS L'OREAL (FR) 2001-01-10 EP disclosed
WO-2000043368-A1 NOVEL CATIONIC 2-ACYLAMINOPHENOLS, THEIR USE AS COUPLER FOR OXIDATION DYEING, COMPOSITIONS CONTAINING THEM, AND DYEING METHODS L'OREAL (FR) 2000-07-27 WO disclosed
US-5334225-A Imparts color tone of high chroma; excellent in coloring power and fastness KAO CORPORATION (JP) 1994-08-02 US disclosed
EP-0579204-A2 Dye composition for a keratinous fiber KAO CORPORATION (JP) 1994-01-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11230680-B2 Methods for preparing fuel additives ADH1A, ADH1C, HOGA1 ALDH1A1 130/4885HTT 2089/4885SMN1; SMN2 1523/4885
US-20200332208-A1 Methods for Preparing Fuel Additives ADH1A, ADH1C, HOGA1 ALDH1A1 130/4885HTT 2089/4885SMN1; SMN2 1523/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.