Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.39 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.39 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.39 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4089162 | 0.85 | CA2 (0.53) | HRH3CA2CA12CA1CA7 | |
| SCHEMBL13724698 | 0.83 | HRH3 (0.44) | HRH3HTR1ADRD2HTR2ADRD3 | |
| SCHEMBL8637757 | 0.82 | CA2 (0.61) | CA2CA12CA1CA7CA13 | |
| SCHEMBL4904511 | 0.79 | TAAR1 (0.50) | HRH3HTR1ADRD2HTR2ADRD3 | |
| SCHEMBL13799440 | 0.79 | AR (0.50) | HRH3CA2CA12CA1CA7 | |
| SCHEMBL23867049 | 0.79 | HRH3 (0.49) | HRH3HTR1ADRD2HTR2ADRD3 | |
| SCHEMBL10684156 | 0.79 | ALDH1A1 (0.55) | HRH3CA2CA12CA1CA7 | |
| SCHEMBL4190589 | 0.79 | HRH3 (0.49) | HRH3HTR1ADRD2HTR2ADRD3 | |
| SCHEMBL3260495 | 0.79 | CA2 (0.47) | HRH3CA2CA12CA1CA7 | |
| SCHEMBL28367599 | 0.78 | HRH3 (0.46) | HRH3HTR1ADRD2HTR2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100137608-A1 | POLY-N-HETEROCYCLIC CARBENE TRANSITION METAL COMPLEXES AND N-HETEROCYCLIC CARBENE TRANSITION METAL COMPLEXES FOR CARBON-SULFUR AND CARBON-OXYGEN COUPLING REACTIONS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2010-06-03 | — | — | US | disclosed |
| US-20100137608-A1 | POLY-N-HETEROCYCLIC CARBENE TRANSITION METAL COMPLEXES AND N-HETEROCYCLIC CARBENE TRANSITION METAL COMPLEXES FOR CARBON-SULFUR AND CARBON-OXYGEN COUPLING REACTIONS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2010-06-03 | — | — | US | disclosed |
| US-6759511-B2 | A CARBONIC ACID 4-NITRO-PHENYL ESTER 2-(4-TRIFLULOROMETHYL-PHENYLSULFANYL)-ETHYL ESTER AS CHEMICAL INTERMEDIATES; AMIDATION, CARBOXYLATION, SULFONATION | HANCHEM CO., LTD. (KR) | 2004-07-06 | — | — | US | disclosed |
| US-20030220469-A1 | Novel compound used as an amino-protecting group, process for preparing the same, and synthetic method of a peptide using the same | HANCHEM CO., LTD. (KR) | 2003-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137608-A1 | POLY-N-HETEROCYCLIC CARBENE TRANSITION METAL COMPLEXES AND N-HETEROCYCLIC CARBENE TRANSITION METAL COMPLEXES FOR CARBON-SULFUR AND CARBON-OXYGEN COUPLING REACTIONS | SCO2, CYCS, NCLN | HRH3 1138/4885CA2 262/4885CA12 159/4885 |
| US-20030220469-A1 | Novel compound used as an amino-protecting group, process for preparing the same, and synthetic method of a peptide using the same | NGLY1, VIP, BCAT2 | HRH3 3532/4885CA2 445/4885CA12 280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.