Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 7/20 | 0.39 |
| ▸ | AR | P10275 | 5/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | ESRRA | P11474 | 4/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6835194 | 0.86 | MRGPRX4 (0.41) | ARDAO | |
| SCHEMBL6835197 | 0.79 | ALDH1A1 (0.38) | — | |
| SCHEMBL6835174 | 0.77 | TAAR1 (0.38) | DAO | |
| SCHEMBL7066297 | 0.77 | POLQ (0.37) | POLQARDAOESRRA | |
| SCHEMBL6824476 | 0.74 | MRGPRX4 (0.39) | ARDAO | |
| SCHEMBL6840001 | 0.72 | LMNA (0.31) | — | |
| SCHEMBL5929043 | 0.72 | RXRA (0.51) | POLQARDAOESRRACES2 | |
| SCHEMBL6840030 | 0.71 | KIF11 (0.40) | ARDAO | |
| SCHEMBL13644756 | 0.70 | POLQ (0.46) | POLQDAOCES2 | |
| SCHEMBL147650 | 0.69 | DAO (0.46) | POLQDAOCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142821-A1 | Pesticide composition comprising malononitrile compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142821-A1 | Pesticide composition comprising malononitrile compounds | CBR1, CBR3, ME1 | POLQ 4743/4885AR 1979/4885DAO 1631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.