Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.62 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.62 |
| ▸ | DRD2 | P14416 | 3/20 | 0.62 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.62 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.62 |
| ▸ | HTR2A | P28223 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.53 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL684364 | 0.94 | HTR1A (0.66) | HTR1ACHRM1ADRA1ADRD2ADRA1D | |
| SCHEMBL684015 | 0.86 | LMNA (0.49) | HTR1ACHRM1ADRA1ADRD2ADRA1D | |
| SCHEMBL683710 | 0.84 | HTR2A (0.73) | HTR1ACHRM1ADRA1ADRD2ADRA1D | |
| Hydrochloric Acid SCHEMBL2796668 | 0.81 | HTR1A (0.61) | HTR1ACHRM1ADRA1ADRD2ADRA1D | |
| SCHEMBL682817 | 0.81 | LMNA (0.62) | DRD2MAPK1LMNASMN1; SMN2RXFP1 | |
| Hydroxyzine SCHEMBL7208301 | 0.80 | HTR2A (0.66) | HTR1ACHRM1ADRA1ADRD2ADRA1D | |
| SCHEMBL683655 | 0.78 | HTR7 (0.77) | HTR1AHTR2AMAPK1LMNAKMT2A | |
| SCHEMBL684006 | 0.78 | CHRM2 (0.72) | HTR1ACHRM1ADRA1ADRD2ADRA1D | |
| SCHEMBL684356 | 0.78 | HTR7 (0.58) | MAPK1LMNASMN1; SMN2RXFP1ADORA2B | |
| SCHEMBL684071 | 0.77 | HTR2A (0.81) | HTR1ACHRM1ADRA1ADRD2ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110269717-A1 | NEUROGENESIS BY MODULATING ANGIOTENSIN | BRAINCELLS INC. (US) | 2011-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269717-A1 | NEUROGENESIS BY MODULATING ANGIOTENSIN | NGF, DCX, BDNF | HTR1A 1265/4885CHRM1 1036/4885ADRA1A 557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.