Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.51 |
| ▸ | HTR2A | P28223 | 5/20 | 0.51 |
| ▸ | HTR2C | P28335 | 5/20 | 0.51 |
| ▸ | HTR2B | P41595 | 5/20 | 0.51 |
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13004977 | 0.87 | SIGMAR1 (0.62) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL14409344 | 0.86 | HTR2A (0.53) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL8779124 | 0.84 | HTR2A (0.51) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL6840810 | 0.80 | SIGMAR1 (0.51) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL6799152 | 0.79 | METAP1 (0.49) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL6841582 | 0.78 | SIGMAR1 (0.47) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL6840788 | 0.78 | SIGMAR1 (0.60) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL2819403 | 0.78 | SMN1; SMN2 (0.51) | SMN1; SMN2METAP1MAOBCYP19A1PRNP | |
| SCHEMBL6801984 | 0.77 | SIGMAR1 (0.54) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL6840779 | 0.76 | SIGMAR1 (0.64) | SIGMAR1HTR2AHTR2CHTR2BDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040266802-A1 | Tricyclic analgesics | CALVET ALAIN (US) | 2004-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040266802-A1 | Tricyclic analgesics | OPRM1, OPRL1, OPRD1 | SIGMAR1 11/4885HTR2A 281/4885HTR2C 96/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.