Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15019990 | 0.79 | RXFP1 (0.34) | TGFBR1RXFP1PIK3CDTDP1ALDH1A1 | |
| SCHEMBL6232122 | 0.78 | PIK3CD (0.45) | TGFBR1RXFP1PIK3CDTDP1KDM4E | |
| SCHEMBL21252699 | 0.75 | PIK3CD (0.34) | TGFBR1RXFP1PIK3CDALDH1A1 | |
| SCHEMBL2392745 | 0.73 | TGFBR1 (0.40) | TGFBR1RXFP1KDM4EALDH1A1 | |
| Bromide SCHEMBL9456283 | 0.73 | CA1 (0.38) | — | |
| SCHEMBL491400 | 0.72 | TDP1 (0.35) | TGFBR1TDP1KDM4EALDH1A1 | |
| SCHEMBL9682306 | 0.71 | RXFP1 (0.34) | TGFBR1RXFP1PIK3CDTDP1ALDH1A1 | |
| SCHEMBL3422991 | 0.71 | ALDH1A1 (0.34) | TGFBR1TDP1ALDH1A1 | |
| SCHEMBL31616195 | 0.70 | TGFBR1 (0.34) | TGFBR1RXFP1 | |
| SCHEMBL11139937 | 0.69 | TGFBR1 (0.32) | TGFBR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040009145-A1 | IONIC POLYMERS AS TOXIN-BINDING AGENTS | GELTEX PHARMACEUTICALS, INC. | 2004-01-15 | — | — | US | disclosed |
| US-20020114774-A1 | Ionic polymers as toxin-binding agents | GELTEX PHARMACEUTICALS, INC. | 2002-08-22 | — | — | US | disclosed |
| US-6290947-B1 | IN ONE EMBODIMENT, THE POLYMER IS A COPOLYMER COMPRISING A MONOMER HAVING A PENDANT AMMONIUM GROUP AND A HYDROPHOBIC MONOMER. | GELTEX PHARMACEUTICALS, INC. | 2001-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020114774-A1 | Ionic polymers as toxin-binding agents | PIGS, ANTXR2, MSN | TGFBR1 3424/4885RXFP1 1745/4885PIK3CD 4246/4885 |
| US-20040009145-A1 | IONIC POLYMERS AS TOXIN-BINDING AGENTS | PIGS, ANTXR2, MSN | TGFBR1 3424/4885RXFP1 1745/4885PIK3CD 4246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.