Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | XIAP | P98170 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29543137 | 0.88 | POLB (0.49) | LMNAPOLBKMT2APKMMAPT | |
| SCHEMBL450849 | 0.88 | SLC7A5 (0.61) | LMNAPOLBKMT2APKMMAPT | |
| SCHEMBL22645606 | 0.88 | SLC7A5 (0.61) | LMNAPOLBKMT2APKMMAPT | |
| SCHEMBL671002 | 0.88 | SLC7A5 (0.61) | LMNAPOLBKMT2APKMMAPT | |
| SCHEMBL28506588 | 0.86 | SLC6A4 (0.59) | LMNAPOLBKMT2ASLC6A2SLC6A3 | |
| SCHEMBL14478245 | 0.86 | SLC6A4 (0.59) | LMNAPOLBKMT2ASLC6A2SLC6A3 | |
| SCHEMBL1969572 | 0.85 | ALDH1A1 (0.48) | LMNAPOLBKMT2APKMMAPT | |
| SCHEMBL12104023 | 0.84 | LDHA (0.62) | POLBLDHASLC6A4 | |
| SCHEMBL13113076 | 0.84 | LDHA (0.62) | POLBLDHASLC6A4 | |
| SCHEMBL4655986 | 0.84 | LDHA (0.62) | POLBLDHASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8940791-B2 | Acetylated amino acids as anti-platelet agents, nutritional and vitamin supplements | SIGNATURE R&D HOLDINGS, LLC (US) | 2015-01-27 | — | — | US | disclosed |
| US-20140200256-A1 | Acetylated amino acids as Anti-platelet agents, Nutritional And Vitamin Supplements | SIGNATURE R&D HOLDINGS, LLC (US) | 2014-07-17 | — | — | US | disclosed |
| US-20110312890-A1 | ACETYLATED AMINO ACIDS AS ANTI-PLATELET AGENTS, NUTRITIONAL AND VITAMIN SUPPLEMENTS | SIGNATURE R&D HOLDINGS, LLC (US) | 2011-12-22 | — | — | US | disclosed |
| US-20110275713-A1 | Acetylated amino acids as Anti-platelet agents, Nutritional And Vitamin Supplements | SIGNATURE R&D HOLDINGS, LLC (US) | 2011-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140200256-A1 | Acetylated amino acids as Anti-platelet agents, Nutritional And Vitamin Supplements | PLTP, GP6, PDGFA | LMNA 3519/4885POLB 3209/4885KMT2A 1202/4885 |
| US-20110312890-A1 | ACETYLATED AMINO ACIDS AS ANTI-PLATELET AGENTS, NUTRITIONAL AND VITAMIN SUPPLEMENTS | PLTP, GP6, PDGFA | LMNA 3519/4885POLB 3209/4885KMT2A 1202/4885 |
| US-20110275713-A1 | Acetylated amino acids as Anti-platelet agents, Nutritional And Vitamin Supplements | PLTP, GP6, PDGFA | LMNA 3519/4885POLB 3209/4885KMT2A 1202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.