Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | LOX | P28300 | 1/20 | 0.44 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28572896 | 0.84 | LMNA (0.45) | MEN1KMT2AHTTL3MBTL1LMNA | |
| SCHEMBL3298310 | 0.82 | MEN1 (0.44) | MEN1KMT2AHTTL3MBTL1LMNA | |
| SCHEMBL15939581 | 0.82 | GABRP (0.54) | MEN1KMT2AHTTL3MBTL1LMNA | |
| SCHEMBL28580081 | 0.82 | LOXL2 (0.44) | LOXL2MEN1KMT2AHTTL3MBTL1 | |
| SCHEMBL23358048 | 0.80 | RECQL (0.51) | RECQLLOXLOXL3LOXL2MEN1 | |
| SCHEMBL17371937 | 0.79 | MEN1 (0.50) | RECQLMEN1KMT2AHTTL3MBTL1 | |
| SCHEMBL568131 | 0.79 | MEN1 (0.40) | MEN1KMT2AHTTL3MBTL1LMNA | |
| SCHEMBL17371971 | 0.79 | CTSK (0.40) | MEN1KMT2AHTTL3MBTL1LMNA | |
| SCHEMBL25302150 | 0.79 | LOXL2 (0.40) | RECQLLOXLOXL3LOXL2 | |
| SCHEMBL2065633 | 0.78 | ALDH1A1 (0.51) | MEN1KMT2AHTTL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1814871-B1 | COMPOUNDS THAT MODULATE PPARY TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RES & DEV (FR) | 2011-03-02 | — | — | EP | disclosed |