Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.50 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.46 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6799182 | 0.80 | JUN (0.48) | ALDH1A1NPSR1PIK3CAPIK3R1AR | |
| SCHEMBL18412843 | 0.73 | ALDH1A1 (0.51) | ALDH1A1NPSR1MEN1KMT2APIK3CA | |
| SCHEMBL18412858 | 0.72 | PRKDC (0.48) | ALDH1A1NPSR1L3MBTL1LMNATDP1 | |
| SCHEMBL6804364 | 0.72 | PRKDC (0.48) | ALDH1A1NPSR1LMNAPIK3CAPIK3R1 | |
| SCHEMBL18412859 | 0.70 | PRKDC (0.46) | ALDH1A1NPSR1LMNAMEN1KMT2A | |
| SCHEMBL18412857 | 0.70 | ALDH1A1 (0.48) | ALDH1A1NPSR1LMNAPIK3CAPIK3R1 | |
| SCHEMBL9374034 | 0.68 | KDM4E (0.73) | ALDH1A1L3MBTL1LMNAKMT2ACYP3A4 | |
| SCHEMBL18412862 | 0.68 | PRKDC (0.44) | ALDH1A1NPSR1LMNAMEN1KMT2A | |
| SCHEMBL6798831 | 0.67 | CDC7 (0.43) | ALDH1A1MEN1KMT2ACYP2C9MAPT | |
| SCHEMBL6803709 | 0.66 | PLOD2 (0.42) | ALDH1A1MEN1KMT2ACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142976-A1 | Pyridylfuran and pyridylthiophene compounds | PFIZER INC. | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142976-A1 | Pyridylfuran and pyridylthiophene compounds | MC2R, FCGR2A, OGFR | ALDH1A1 789/4885NPSR1 179/4885L3MBTL1 3138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.