Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 4/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6842678 | 0.91 | MMP13 (0.65) | MMP13NR1H4RAB9APTGER4CYP3A4 | |
| SCHEMBL6843413 | 0.89 | NR1H4 (0.52) | MMP13NR1H4NPC1RAB9AEPHX2 | |
| SCHEMBL6842635 | 0.89 | NR1H4 (0.59) | MMP13NR1H4KMT2AEPHX2MEN1 | |
| SCHEMBL6838326 | 0.87 | EPHX2 (0.50) | NR1H4EPHX2ALDH1A1SMN1; SMN2PTGER4 | |
| SCHEMBL6845318 | 0.87 | NR1H4 (0.51) | MMP13NR1H4EPHX2L3MBTL1PTGER4 | |
| SCHEMBL6843478 | 0.87 | EPHX2 (0.52) | NR1H4RAB9AKMT2AEPHX2MEN1 | |
| SCHEMBL6843325 | 0.87 | NR1H4 (0.51) | MMP13NR1H4KMT2AEPHX2MEN1 | |
| SCHEMBL6843206 | 0.87 | NR1H4 (0.51) | MMP13NR1H4EPHX2HDAC1ALDH1A1 | |
| SCHEMBL6845364 | 0.86 | NR1H4 (0.50) | MMP13NR1H4EPHX2SMN1; SMN2CYP3A4 | |
| SCHEMBL6838118 | 0.86 | MMP13 (0.55) | MMP13NR1H4NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040043983-A1 | Naphthalene derivatives as matrix metalloproteinase inhibitors | LI JIE JACK (US) | 2004-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040043983-A1 | Naphthalene derivatives as matrix metalloproteinase inhibitors | MMP9, MMP8, MMP13 | MMP13 3/4885NR1H4 1615/4885NPC1 267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.