Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 4/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6843386 | 0.89 | CA1 (0.41) | ALDH1A1TSHRCA12CA1CA2 | |
| SCHEMBL6842640 | 0.88 | ALDH1A1 (0.48) | ALDH1A1TSHRKMT2AMAPK1MEN1 | |
| SCHEMBL6845362 | 0.88 | CA1 (0.42) | ALDH1A1TSHRKMT2AMEN1CA12 | |
| SCHEMBL6842383 | 0.87 | CA1 (0.55) | CA12CA1CA2CA9CA14 | |
| SCHEMBL6843238 | 0.86 | ALDH1A1 (0.55) | ALDH1A1TSHRKMT2AMAPK1MEN1 | |
| SCHEMBL6838252 | 0.86 | ALDH1A1 (0.53) | ALDH1A1TSHRKMT2AMAPK1MEN1 | |
| SCHEMBL6843419 | 0.84 | RXRA (0.43) | ALDH1A1KMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL6194312 | 0.83 | MAPT (0.50) | ALDH1A1KMT2AMAPTRXRASMN1; SMN2 | |
| SCHEMBL6198198 | 0.83 | NPC1 (0.50) | ALDH1A1CA1CA2POLBMAPT | |
| SCHEMBL6195444 | 0.82 | ALDH1A1 (0.56) | ALDH1A1KMT2AMAPK1MEN1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040043983-A1 | Naphthalene derivatives as matrix metalloproteinase inhibitors | LI JIE JACK (US) | 2004-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040043983-A1 | Naphthalene derivatives as matrix metalloproteinase inhibitors | MMP9, MMP8, MMP13 | ALDH1A1 1588/4885TSHR 3787/4885KMT2A 4149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.