Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ADH1B | P00325 | 1/20 | 0.36 |
| ▸ | ADH1C | P00326 | 1/20 | 0.36 |
| ▸ | ADH1A | P07327 | 1/20 | 0.36 |
| ▸ | ADH7 | P40394 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 3/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL684331 | 0.82 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2LMNAHTTCDC25A | |
| SCHEMBL6137421 | 0.82 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2LMNAHTTCDC25A | |
| SCHEMBL6137423 | 0.82 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2LMNAHTTCDC25A | |
| SCHEMBL6330349 | 0.78 | CDC25A (0.41) | ALDH1A1SMN1; SMN2LMNAHTTCDC25A | |
| SCHEMBL6330352 | 0.78 | CDC25A (0.41) | ALDH1A1SMN1; SMN2LMNAHTTCDC25A | |
| Fimbrolide SCHEMBL13668734 | 0.73 | CDC25A (0.38) | CDC25ACDC25BCDC25C | |
| SCHEMBL20013939 | 0.71 | CDC25A (0.33) | CDC25ACDC25BCDC25C | |
| SCHEMBL6331065 | 0.68 | CDC25A (0.46) | ALDH1A1CDC25ACDC25BCDC25C | |
| SCHEMBL6331066 | 0.68 | CDC25A (0.46) | ALDH1A1CDC25ACDC25BCDC25C | |
| SCHEMBL13372032 | 0.67 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2LMNAHTTCDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2177226-B1 | Hydroxamate compositions | COVIDIEN LP (US) | 2013-09-18 | — | — | EP | disclosed |
| US-8425972-B2 | Antimicrobial materials and coatings | COVIDIEN LP (US) | 2013-04-23 | — | — | US | disclosed |
| US-8425972-B2 | Antimicrobial materials and coatings | COVIDIEN LP (US) | 2013-04-23 | — | — | US | disclosed |
| EP-2564859-A1 | Hydroxamate compositions | Covidien LP (US) | 2013-03-06 | — | — | EP | disclosed |
| US-8153741-B2 | Furanone copolymers | TYCO HEALTHCARE GROUP LP (US) | 2012-04-10 | — | — | US | disclosed |
| US-8153741-B2 | Furanone copolymers | TYCO HEALTHCARE GROUP LP (US) | 2012-04-10 | — | — | US | disclosed |
| US-20110280824-A1 | Furanone Copolymers | TYCO HEALTHCARE GROUP LP (US) | 2011-11-17 | — | — | US | disclosed |
| US-20110280824-A1 | Furanone Copolymers | TYCO HEALTHCARE GROUP LP (US) | 2011-11-17 | — | — | US | disclosed |
| US-7999051-B2 | Furanone copolymers | TYCO HEALTHCARE GROUP LP (US) | 2011-08-16 | — | — | US | disclosed |
| US-7999051-B2 | Furanone copolymers | TYCO HEALTHCARE GROUP LP (US) | 2011-08-16 | — | — | US | disclosed |
| US-7923439-B2 | Hydroxamate compositions | TYCO HEALTHCARE GROUP LP (US) | 2011-04-12 | — | — | US | disclosed |
| US-7923439-B2 | Hydroxamate compositions | TYCO HEALTHCARE GROUP LP (US) | 2011-04-12 | — | — | US | disclosed |
| US-20100130713-A1 | FURANONE COPOLYMERS | COVIDIEN LP | 2010-05-27 | — | — | US | disclosed |
| US-20100130713-A1 | FURANONE COPOLYMERS | COVIDIEN LP | 2010-05-27 | — | — | US | disclosed |
| US-20100119695-A1 | ANTIMICROBIAL MATERIALS AND COATINGS | COVIDIEN LP | 2010-05-13 | — | — | US | disclosed |
| US-20100119695-A1 | ANTIMICROBIAL MATERIALS AND COATINGS | COVIDIEN LP | 2010-05-13 | — | — | US | disclosed |
| EP-2177226-A1 | Hydroxamate compositions | Tyco Healthcare Group LP (US) | 2010-04-21 | — | — | EP | disclosed |
| US-20100093846-A1 | HYDROXAMATE COMPOSITIONS | TYCO HEALTHCARE GROUP LP | 2010-04-15 | — | — | US | disclosed |
| US-20100093846-A1 | HYDROXAMATE COMPOSITIONS | TYCO HEALTHCARE GROUP LP | 2010-04-15 | — | — | US | disclosed |
| WO-2008144247-A1 | ANTIMICROBIAL MATERIALS AND COATINGS | TYCO HEALTHCARE GROUP LP (US) | 2008-11-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110280824-A1 | Furanone Copolymers | PLA2G5, PLA2G2A, PLA2G10 | KMT2A 4450/4885ADH1B 3467/4885ADH1C 3375/4885 |
| US-20100093846-A1 | HYDROXAMATE COMPOSITIONS | HCAR3, ABHD16A, PLA2G2C | KMT2A 2098/4885ADH1B 939/4885ADH1C 2208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.