Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6843227 | 0.89 | CA1 (0.39) | ALDH1A1TSHRPKMKMT2AMAPT | |
| SCHEMBL6843330 | 0.87 | ALDH1A1 (0.49) | ALDH1A1TSHRPKMKMT2AMAPT | |
| SCHEMBL6843461 | 0.87 | CA1 (0.50) | — | |
| SCHEMBL6842923 | 0.86 | CA1 (0.41) | ALDH1A1TSHRKMT2AMAPTMEN1 | |
| SCHEMBL6843235 | 0.85 | ALDH1A1 (0.48) | ALDH1A1TSHRPKMKMT2AMAPT | |
| SCHEMBL6843366 | 0.84 | ALDH1A1 (0.51) | ALDH1A1TSHRKMT2AMAPTMEN1 | |
| SCHEMBL6192360 | 0.84 | LMNA (0.50) | ALDH1A1TSHRKMT2AMAPTMEN1 | |
| SCHEMBL6843226 | 0.84 | ALDH1A1 (0.43) | ALDH1A1TSHRPKMKMT2AMAPT | |
| SCHEMBL6843225 | 0.83 | ALDH1A1 (0.44) | ALDH1A1TSHRPKMKMT2AMAPT | |
| SCHEMBL6197349 | 0.83 | ALDH1A1 (0.52) | ALDH1A1KMT2AMAPTMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040043983-A1 | Naphthalene derivatives as matrix metalloproteinase inhibitors | LI JIE JACK (US) | 2004-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040043983-A1 | Naphthalene derivatives as matrix metalloproteinase inhibitors | MMP9, MMP8, MMP13 | ALDH1A1 1588/4885TSHR 3787/4885PKM 1893/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.