Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27547318 | 0.84 | PARP1 (0.43) | PARP1TDP1KDM4EALDH1A1HPGD | |
| SCHEMBL50426 | 0.75 | KDM4E (0.49) | PARP1TDP1KDM4EALDH1A1HPGD | |
| SCHEMBL10205808 | 0.73 | PARP1 (0.47) | PARP1TDP1KDM4EALDH1A1HPGD | |
| SCHEMBL559163 | 0.73 | PARP1 (0.47) | PARP1TDP1KDM4EALDH1A1HPGD | |
| SCHEMBL8502533 | 0.73 | LMNA (0.57) | TDP1KDM4EMTNR1AMTNR1BLMNA | |
| SCHEMBL8501371 | 0.73 | LMNA (0.57) | TDP1KDM4EMTNR1AMTNR1BLMNA | |
| SCHEMBL2465015 | 0.73 | LMNA (0.57) | TDP1KDM4EMTNR1AMTNR1BLMNA | |
| SCHEMBL559102 | 0.72 | PARP1 (0.46) | PARP1TDP1KDM4EALDH1A1HPGD | |
| SCHEMBL13616708 | 0.72 | POLL (0.49) | PARP1KDM4EALDH1A1HPGDDRD2 | |
| Acetic Acid SCHEMBL355654 | 0.71 | ACHE (0.47) | PARP1TDP1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040102652-A1 | Optically active2-aminotetralin derivatives, the processes for the preparation thereof and the therapeutical use of pharmaceutical compositions containing them | CHIESI FARMACEUTICI S.P.A. (IT) | 2004-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102652-A1 | Optically active2-aminotetralin derivatives, the processes for the preparation thereof and the therapeutical use of pharmaceutical compositions containing them | AADAT, AASDHPPT, AAAS | PARP1 1989/4885TDP1 1780/4885KDM4E 1637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.