SCHEMBL6844262

SCHEMBL6844262

CC(C)(C)c1ccc(-c2cc(O)ccc2C(=O)O)c(C(C)(C)C)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.46
CA12 O43570 3/20 0.42
CA1 P00915 3/20 0.42
CA9 Q16790 3/20 0.42
ALDH1A1 P00352 3/20 0.42
CA2 P00918 2/20 0.42
CA7 P43166 2/20 0.42
CA14 Q9ULX7 2/20 0.42
TSHR P16473 1/20 0.42
HSD17B10 Q99714 3/20 0.41
SERPINE1 P05121 1/20 0.40
AKR1C2 P52895 2/20 0.40
AKR1C1 Q04828 1/20 0.40
RXRB P28702 1/20 0.39
LMNA P02545 2/20 0.39
TYR P14679 2/20 0.39
ALOX15 P16050 2/20 0.39
NR1I2 O75469 1/20 0.39
CYP2C9 P11712 1/20 0.39
MIF P14174 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5582942 0.85 HSD17B10 (0.49) CA12CA1CA9ALDH1A1CA2
SCHEMBL538460 0.82 TDP1 (0.42) TDP1CA12CA1CA9ALDH1A1
SCHEMBL7132396 0.82 ALDH1A1 (0.47) TDP1CA12CA1CA9ALDH1A1
SCHEMBL27904859 0.81 TDP1 (0.56) TDP1ALDH1A1HSD17B10SERPINE1AKR1C2
SCHEMBL4631399 0.81 TDP1 (0.59) TDP1ALDH1A1HSD17B10SERPINE1AKR1C2
SCHEMBL27923138 0.79 TDP1 (0.57) TDP1ALDH1A1HSD17B10SERPINE1AKR1C2
SCHEMBL27888034 0.79 TDP1 (0.57) TDP1ALDH1A1HSD17B10SERPINE1AKR1C2
SCHEMBL8394163 0.78 TDP1 (0.44) TDP1CA12CA1CA9ALDH1A1
SCHEMBL8687536 0.78 HNF4A (0.47) TDP1CA12CA1CA9ALDH1A1
SCHEMBL29654078 0.77 ALDH1A1 (0.57) TDP1CA12CA1CA9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260062580-A1 REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT THE PILOT INK CO., LTD. (JP) 2026-03-05 US disclosed
US-12460099-B2 Reversibly thermochromic composition, reversibly thermochromic microcapsule pigment encapsulating reversibly thermochromic composition, and writing instrument using reversibly thermochromic microcapsule pigment THE PILOT INK CO., LTD. (JP) 2025-11-04 US disclosed
US-12098289-B2 Photochromic composition THE PILOT INK CO., LTD. (JP) 2024-09-24 US disclosed
CN-113646052-B Reversible thermochromic composition, reversible thermochromic microcapsule pigment, and writing instrument 百乐墨水株式会社 2024-05-17 CN disclosed
US-20220169919-A1 REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT THE PILOT INK CO., LTD. (JP) 2022-06-02 US disclosed
US-20220049103-A1 PHOTOCHROMIC COMPOSITION THE PILOT INK CO., LTD. (JP) 2022-02-17 US disclosed
EP-3950068-A1 REVERSIBLE THERMOCHROMIC COMPOSITION, REVERSIBLE THERMOCHROMIC MICROCAPSULE PIGMENT COMPRISING SAME, AND WRITING INSTRUMENT USING SAME THE PILOT INK CO., LTD. (JP) 2022-02-09 EP disclosed
CN-113646052-A Reversible thermal discoloration composition, reversible thermal discoloration microcapsule pigment encapsulating the reversible thermal discoloration composition, and writing instrument using the reversible thermal discoloration microcapsule pigment 百乐墨水株式会社 2021-11-12 CN disclosed
WO-2020203603-A1 REVERSIBLE THERMOCHROMIC COMPOSITION, REVERSIBLE THERMOCHROMIC MICROCAPSULE PIGMENT COMPRISING SAME, AND WRITING INSTRUMENT USING SAME パイロットインキ株式会社 2020-10-08 WO disclosed
CN-111527442-A System and method for customizing photochromic articles 光学转变有限公司 2020-08-11 CN disclosed
WO-2020137469-A1 PHOTOCHROMIC COMPOSITION パイロットインキ株式会社 2020-07-02 WO disclosed
EP-2949697-B1 RESIN COMPOSITION ADEKA CORP (JP) 2018-01-31 EP disclosed
US-9624355-B2 Resin composition ADEKA CORPORATION (JP) 2017-04-18 US disclosed
US-20150353710-A1 RESIN COMPOSITION ADEKA CORPORATION (JP) 2015-12-10 US disclosed
EP-2949697-A1 RESIN COMPOSITION Adeka Corporation (JP) 2015-12-02 EP disclosed
US-6770125-B2 Reversible thermochromic composition NEW PRISMATIC ENTERPRISE CO., LTD. (TW) 2004-08-03 US disclosed
US-20030121448-A1 Reversible thermochromic composition NEW PRISMATIC ENTERPRISE CO., LTD. (TW) 2003-07-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260062580-A1 REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT TYR, SCO2, HBB TDP1 1338/4885CA12 3080/4885CA1 4057/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.