Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 4/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15049708 | 0.76 | HCAR3 (0.63) | HCAR3ALDH1A1MAPTNPSR1HTT | |
| SCHEMBL28715157 | 0.75 | IDO1 (0.52) | HCAR3IDO1ALDH1A1MAPTNPSR1 | |
| SCHEMBL5821559 | 0.75 | HCAR3 (0.48) | HCAR3ALDH1A1MAPTNPSR1HTT | |
| SCHEMBL18676266 | 0.74 | ALDH1A1 (0.55) | HCAR3IDO1ALDH1A1MAPTNPSR1 | |
| SCHEMBL7155802 | 0.74 | ALOX15 (0.51) | MAPTALOX12BACE1ALOX15ESR1 | |
| SCHEMBL182012 | 0.74 | HCAR3 (0.49) | HCAR3ALDH1A1MAPTNPSR1HTT | |
| SCHEMBL7098819 | 0.73 | ALDH3A1 (0.47) | HCAR3ALDH1A1MAPTNPSR1HTT | |
| SCHEMBL9760048 | 0.72 | HCAR3 (0.47) | HCAR3ALDH1A1MAPTNPSR1HTT | |
| SCHEMBL688642 | 0.72 | HCAR3 (0.51) | HCAR3ALDH1A1MAPTNPSR1HTT | |
| SCHEMBL16097975 | 0.72 | ALDH1A1 (0.53) | HCAR3IDO1ALDH1A1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1430874-A2 | 4-N, N-Bis-(monohydroxyalkyl)amino-3-nitrophenol derivatives in dyeing compositions for keratinic fibres | Henkel Kommanditgesellschaft auf Aktien (DE) | 2004-06-23 | — | — | EP | claimed |
| EP-1430874-A2 | 4-N, N-Bis-(monohydroxyalkyl)amino-3-nitrophenol derivatives in dyeing compositions for keratinic fibres | Henkel Kommanditgesellschaft auf Aktien (DE) | 2004-06-23 | — | — | EP | disclosed |