Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | TBXAS1 | P24557 | 9/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6195895 | 0.87 | KMT2A (0.53) | KMT2ALMNATDP1ALDH1A1MEN1 | |
| SCHEMBL6845187 | 0.86 | KMT2A (0.48) | KMT2ALMNATDP1TBXAS1HDAC1 | |
| SCHEMBL10626415 | 0.84 | TBXAS1 (0.53) | KMT2ATBXAS1ALDH1A1MEN1TP53 | |
| SCHEMBL10627493 | 0.81 | TBXAS1 (0.54) | KMT2ATBXAS1ALDH1A1MEN1TP53 | |
| SCHEMBL6843398 | 0.81 | KMT2A (0.46) | KMT2ALMNATDP1TBXAS1HDAC1 | |
| SCHEMBL6244954 | 0.80 | MAPT (0.50) | KMT2ALMNATDP1ALDH1A1MEN1 | |
| SCHEMBL6193156 | 0.80 | NR4A2 (0.50) | KMT2ALMNATDP1ALDH1A1MEN1 | |
| SCHEMBL6194401 | 0.80 | RXRA (0.50) | KMT2ALMNATDP1ALDH1A1MEN1 | |
| SCHEMBL6192600 | 0.80 | RXRA (0.50) | KMT2ALMNATDP1ALDH1A1MEN1 | |
| SCHEMBL6193636 | 0.80 | SRD5A2 (0.54) | KMT2ALMNAALDH1A1MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040043983-A1 | Naphthalene derivatives as matrix metalloproteinase inhibitors | LI JIE JACK (US) | 2004-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040043983-A1 | Naphthalene derivatives as matrix metalloproteinase inhibitors | MMP9, MMP8, MMP13 | KMT2A 4149/4885LMNA 1548/4885TDP1 1549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.