Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | RXRB | P28702 | 1/20 | 0.45 |
| ▸ | RXRG | P48443 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 2/20 | 0.38 |
| ▸ | VKORC1 | Q9BQB6 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.37 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6211543 | 0.89 | MRGPRX4 (0.40) | RXRARXRBRXRGMEN1KMT2A | |
| SCHEMBL6842430 | 0.89 | MAPT (0.44) | ALDH1A1NR4A2MMP12MMP1MEN1 | |
| SCHEMBL6195785 | 0.89 | LMNA (0.48) | ALDH1A1MEN1KMT2ASLC6A2 | |
| SCHEMBL6845496 | 0.88 | MAPT (0.42) | ALDH1A1MEN1KMT2A | |
| SCHEMBL6843440 | 0.87 | RXRA (0.43) | RXRARXRBALDH1A1MEN1KMT2A | |
| SCHEMBL6843367 | 0.87 | RXRA (0.43) | RXRARXRBALDH1A1MMP1MEN1 | |
| SCHEMBL6843319 | 0.87 | SRD5A2 (0.43) | SRD5A2ALDH1A1MEN1KMT2A | |
| SCHEMBL6838144 | 0.87 | NR4A2 (0.43) | RXRARXRBRXRGALDH1A1NR4A2 | |
| SCHEMBL6843022 | 0.86 | SRD5A2 (0.48) | SRD5A2RXRARXRBRXRGALDH1A1 | |
| SCHEMBL6211990 | 0.85 | PTPN5 (0.47) | RXRARXRBALDH1A1MAOBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040043983-A1 | Naphthalene derivatives as matrix metalloproteinase inhibitors | LI JIE JACK (US) | 2004-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040043983-A1 | Naphthalene derivatives as matrix metalloproteinase inhibitors | MMP9, MMP8, MMP13 | SRD5A2 254/4885RXRA 2850/4885RXRB 2848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.