Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | POLB | P06746 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.60 |
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | STAT3 | P40763 | 1/20 | 0.59 |
| ▸ | LCK | P06239 | 1/20 | 0.58 |
| ▸ | ITGB2 | P05107 | 4/20 | 0.58 |
| ▸ | ITGAM | P11215 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | APEX1 | P27695 | 2/20 | 0.57 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.55 |
| ▸ | PTPN22 | Q9Y2R2 | 2/20 | 0.54 |
| ▸ | PSMB8 | P28062 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16687571 | 0.89 | ENPP2 (0.82) | ENPP2TDP1MEN1POLBKMT2A | |
| SCHEMBL5146767 | 0.82 | STAT3 (0.80) | ENPP2TDP1MEN1POLBKMT2A | |
| SCHEMBL5146772 | 0.82 | STAT3 (0.80) | ENPP2TDP1MEN1POLBKMT2A | |
| SCHEMBL5144867 | 0.82 | PTPN22 (0.75) | ENPP2TDP1MEN1POLBKMT2A | |
| SCHEMBL46552 | 0.82 | PTPN22 (0.75) | ENPP2TDP1MEN1POLBKMT2A | |
| SCHEMBL4892925 | 0.81 | STAT3 (0.75) | ENPP2TDP1MEN1POLBKMT2A | |
| SCHEMBL4892919 | 0.81 | STAT3 (0.75) | ENPP2TDP1MEN1POLBKMT2A | |
| SCHEMBL17715075 | 0.80 | ENPP2 (0.69) | ENPP2TDP1MEN1POLBKMT2A | |
| SCHEMBL46549 | 0.80 | ITGB2 (0.63) | ENPP2TDP1MEN1POLBKMT2A | |
| SCHEMBL684272 | 0.80 | ENPP2 (0.83) | ENPP2TDP1MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120010255-A1 | Compounds and Methods for Regulating Integrins | ATEGRIN, INC. | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010255-A1 | Compounds and Methods for Regulating Integrins | ITGB8, ITGB3, ITGAM | ENPP2 1581/4885TDP1 4431/4885MEN1 1586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.