SCHEMBL6845944

SCHEMBL6845944

Cl[Si](Cl)(Cl)CC(c1ccccc1)[Si](Cl)(Cl)Cl

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39
HTR2A P28223 2/20 0.36
TAAR1 Q96RJ0 1/20 0.36
SRC P12931 1/20 0.34
AOC3 Q16853 4/20 0.33
SLC6A4 P31645 3/20 0.33
SLC6A3 Q01959 3/20 0.33
DPP4 P27487 2/20 0.33
SLC6A2 P23975 2/20 0.33
HRH1 P35367 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
MTOR P42345 1/20 0.33
RAB9A P51151 1/20 0.33
GRM7 Q14831 1/20 0.33
F2 P00734 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6848493 0.88 PGK1 (0.32)
SCHEMBL6848491 0.79
SCHEMBL6845943 0.78 CHRNA7 (0.35) CYP3A4CYP2D6CYP2C19
SCHEMBL8204424 0.78 HTR2A (0.46) TSHRHTR2ATAAR1SLC6A4SLC6A3
SCHEMBL3794550 0.77 LMNA (0.46) TSHRHTR2ATAAR1AOC3HRH1
SCHEMBL28704914 0.76 SLC6A2 (0.48) TSHRHTR2ATAAR1SLC6A4SLC6A3
SCHEMBL1504701 0.74 TSHR (0.46) TSHRHTR2ATAAR1AOC3SLC6A4
SCHEMBL3444925 0.74 AOC3 (0.42) TSHRHTR2ATAAR1AOC3HRH1
SCHEMBL5413664 0.73 TAAR1 (0.52) TSHRTAAR1AOC3
SCHEMBL2101611 0.71 TSHR (0.37) TSHRHTR2ATAAR1AOC3SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040082803-A1 Trichlorosilyl groups containing organochlorosilanes and their preparation methods by the double-silylation of olefins with trichlorosilane KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY 2004-04-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040082803-A1 Trichlorosilyl groups containing organochlorosilanes and their preparation methods by the double-silylation of olefins with trichlorosilane CBR1, OXSR1, HCCS TSHR 182/4885HTR2A 4385/4885TAAR1 123/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.