SCHEMBL684673

SCHEMBL684673

COc1ccc(C(=O)N/N=C(\C)c2cccc(OC)c2O)cc1

nearest known ligand 0.57

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.57
RAB9A P51151 8/20 0.57
KDM4E B2RXH2 4/20 0.57
MAPT P10636 7/20 0.56
CYP1A2 P05177 1/20 0.56
NPC1 O15118 8/20 0.55
KDM1A O60341 1/20 0.53
SMN1; SMN2 Q16637 6/20 0.52
ALDH1A1 P00352 4/20 0.51
PSMD14 O00487 1/20 0.51
HPGD P15428 1/20 0.51
KLK1 P06870 1/20 0.47
KLK5 Q9Y337 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19283315 0.91 KDM1A (0.65) GAARAB9AKDM4EMAPTNPC1
SCHEMBL19283317 0.91 KDM1A (0.65) GAARAB9AKDM4EMAPTNPC1
SCHEMBL685003 0.90 RAB9A (0.56) GAARAB9AKDM4EMAPTCYP1A2
SCHEMBL684593 0.90 NPC1 (0.60) GAARAB9AKDM4EMAPTCYP1A2
SCHEMBL684710 0.89 LMNA (0.55) GAARAB9AKDM4EMAPTCYP1A2
SCHEMBL685319 0.89 SMN1; SMN2 (0.58) RAB9AKDM4EMAPTCYP1A2NPC1
SCHEMBL684831 0.88 GAA (0.55) GAARAB9AKDM4EMAPTCYP1A2
SCHEMBL684677 0.86 KDM1A (0.50) GAARAB9AMAPTCYP1A2NPC1
SCHEMBL10197509 0.86 GAA (0.54) GAARAB9AKDM4EMAPTCYP1A2
SCHEMBL685151 0.85 GAA (0.55) GAARAB9AKDM4EMAPTCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8476194-B2 Fungicidal compositions including hydrazone derivatives and copper DOW AGROSCIENCES, LLC (US) 2013-07-02 US disclosed
US-8476194-B2 Fungicidal compositions including hydrazone derivatives and copper DOW AGROSCIENCES, LLC (US) 2013-07-02 US disclosed
US-20120021066-A1 FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER DOW AGROSCIENCES LLC (US) 2012-01-26 US disclosed
US-20120021066-A1 FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER DOW AGROSCIENCES LLC (US) 2012-01-26 US disclosed
US-20120010075-A1 SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER DOW AGROSCIENCES LLC (US) 2012-01-12 US disclosed
US-20120010075-A1 SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER DOW AGROSCIENCES LLC (US) 2012-01-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120010075-A1 SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER SOD1, CYP51A1, SOD3 GAA 670/4885RAB9A 3846/4885KDM4E 1473/4885
US-20120021066-A1 FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER SOD1, CYP51A1, CYP4Z1 GAA 386/4885RAB9A 3616/4885KDM4E 1286/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.