Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.51 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.51 |
| ▸ | TCF4 | P15884 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21556908 | 0.88 | SCN8A (0.56) | RAB9AL3MBTL1MEN1KMT2ANPSR1 | |
| SCHEMBL19361291 | 0.88 | MMP13 (0.58) | RAB9AL3MBTL1MEN1KMT2ANPSR1 | |
| SCHEMBL18401369 | 0.87 | RAB9A (0.54) | RAB9AL3MBTL1MEN1KMT2ANPSR1 | |
| SCHEMBL27565872 | 0.87 | RAB9A (0.57) | RAB9AL3MBTL1MEN1KMT2ANPSR1 | |
| SCHEMBL2646539 | 0.85 | KAT2B (0.57) | RAB9AGAAHPGDTSHRMAPK1 | |
| SCHEMBL21334373 | 0.84 | RAB9A (0.55) | RAB9AL3MBTL1MEN1KMT2ANPSR1 | |
| SCHEMBL974852 | 0.84 | CTNNB1 (0.62) | RAB9AL3MBTL1MEN1KMT2ANPSR1 | |
| SCHEMBL21556888 | 0.83 | MEN1 (0.49) | RAB9AL3MBTL1MEN1KMT2ANPSR1 | |
| SCHEMBL6689471 | 0.83 | ALDH1A1 (0.64) | RAB9AL3MBTL1MEN1KMT2ANPSR1 | |
| SCHEMBL12376719 | 0.83 | NPSR1 (0.60) | RAB9AL3MBTL1MEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295136-A1 | Analogs of Nitrofuran Antibiotics to Combat Resistance | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA | 2023-09-21 | — | — | US | disclosed |
| CN-109096221-A | The method that the oxidation of catalytic molecular oxygen generates benzoisothiazolinone class compound in water phase | 郑州大学 | 2018-12-28 | — | — | CN | disclosed |
| US-20170312252-A1 | PYRROLIDINE AMIDE COMPOUNDS AS HISTONE DEMETHYLASE INHIBITORS | WUXI APPTEC (SHANGHAI) CO. LTD (CN) | 2017-11-02 | — | — | US | disclosed |
| CN-101130526-B | Aryl carbonyl derivatives as therapeutic agents | NOVO NORDISK AS | 2013-07-10 | — | — | CN | disclosed |
| EP-2113502-A1 | Hydrazyde type compounds and the use thereof in pharmaceutical compositions for the treatment of cardiovascular diseases | Clinigenetics (FR) | 2009-11-04 | — | — | EP | disclosed |
| CN-101130526-A | Aryl carbonyl derivatives as therapeutic agents | NOVO NORDISK AS (DK) | 2008-02-27 | — | — | CN | disclosed |
| US-20070197537-A1 | Heterobicyclic thiophene compounds and methods of use | ARRAY BIOPHARMA, INC. | 2007-08-23 | — | — | US | disclosed |
| CN-1678311-A | Arylcarbonyl derivatives useful as therapeutic agents | NOVO NORDISK AS (DK) | 2005-10-05 | — | — | CN | disclosed |
| US-6756384-B2 | TREATMENT OF DISEASES AND DISORDERS RELATED TO THE HISTAMINE H3 RECEPTOR. | NOVO NORDISK A/S (DK) | 2004-06-29 | — | — | US | disclosed |
| US-20030135056-A1 | Imidazole compounds | HIGH POINT PHARMACEUTICALS, LLC | 2003-07-17 | — | — | US | disclosed |
| EP-1268484-A1 | CONDENSED IMIDAZOLES AS HISTAMINE H3 RECEPTOR LIGANDS | NOVO NORDISK A/S (DK) | 2003-01-02 | — | — | EP | disclosed |
| US-6437147-B1 | FOR THERAPY OF DISEASES OF CENTRAL NERVOUS SYSTEM, PERIPHERAL NERVOUS SYSTEM, CARDIOVASCULAR SYSTEM, PULMONARY SYSTEM, GASTROINTESTINAL SYSTEM AND ENDOCRINOLOGICAL SYSTEM | NOVO NORDISK (DK) | 2002-08-20 | — | — | US | disclosed |
| US-20020058659-A1 | Imidazole compounds | HIGH POINT PHARMACEUTICALS, LLC | 2002-05-16 | — | — | US | disclosed |
| WO-2001068652-A1 | CONDENSED IMIDAZOLES AS HISTAMINE H3 RECEPTOR LIGANDS | NOVO NORDISK A/S (DK) | 2001-09-20 | — | — | WO | disclosed |
| US-4208205-A | Herbicidal benzamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197537-A1 | Heterobicyclic thiophene compounds and methods of use | ERBB2, LCK, SRC | RAB9A 2056/4885L3MBTL1 3393/4885MEN1 3149/4885 |
| US-20230295136-A1 | Analogs of Nitrofuran Antibiotics to Combat Resistance | ATF4, ATF1, FBL | RAB9A 3191/4885L3MBTL1 159/4885MEN1 4351/4885 |
| US-20030135056-A1 | Imidazole compounds | HRH3, HRH4, HRH2 | RAB9A 1533/4885L3MBTL1 3041/4885MEN1 1139/4885 |
| US-20170312252-A1 | PYRROLIDINE AMIDE COMPOUNDS AS HISTONE DEMETHYLASE INHIBITORS | KDM5A, KDM5C, KDM5B | RAB9A 3251/4885L3MBTL1 1933/4885MEN1 3356/4885 |
| US-20020058659-A1 | Imidazole compounds | HRH3, HRH4, HRH2 | RAB9A 1533/4885L3MBTL1 3041/4885MEN1 1139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.