Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.56 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | PNLIP | P16233 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | BRAF | P15056 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.48 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6846935 | 0.88 | RAB9A (0.63) | GAAMEN1KMT2ARAB9AL3MBTL1 | |
| SCHEMBL19361291 | 0.87 | MMP13 (0.58) | GAAMEN1KMT2ARAB9AL3MBTL1 | |
| SCHEMBL18401369 | 0.86 | RAB9A (0.54) | GAAMEN1KMT2ARAB9AL3MBTL1 | |
| SCHEMBL21556888 | 0.85 | MEN1 (0.49) | SCN8ASCN10AGAAMEN1KMT2A | |
| SCHEMBL27850308 | 0.82 | SLC6A3 (0.64) | SCN8ASCN10AGAAMEN1KMT2A | |
| SCHEMBL19524204 | 0.81 | SCN8A (0.53) | SCN8ASCN10AGAAMEN1KMT2A | |
| SCHEMBL2646539 | 0.81 | KAT2B (0.57) | GAARAB9ASMN1; SMN2HPGDKAT2B | |
| SCHEMBL9593924 | 0.80 | PARP10 (0.53) | SCN8ASCN10AGAAKMT2ARAB9A | |
| SCHEMBL2865011 | 0.80 | CTNNB1 (0.58) | SCN8ASCN10AGAAMEN1KMT2A | |
| SCHEMBL9593245 | 0.79 | PARP10 (0.51) | SCN8ASCN10AGAARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3567029-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | Lantheus Medical Imaging, Inc. (US) | 2019-11-13 | — | — | EP | disclosed |