SCHEMBL684752

SCHEMBL684752

O=C(N/N=C/c1c(Cl)ccc(Cl)c1O)c1ccc(Cl)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.56
KDM4E B2RXH2 3/20 0.56
KMT2A Q03164 3/20 0.56
MEN1 O00255 2/20 0.56
LMNA P02545 2/20 0.56
HTT P42858 2/20 0.56
SIRT1 Q96EB6 1/20 0.56
SMN1; SMN2 Q16637 4/20 0.56
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
CA4 P22748 1/20 0.54
CA9 Q16790 1/20 0.54
ALDH1A1 P00352 2/20 0.54
MAPT P10636 2/20 0.54
NPC1 O15118 2/20 0.52
KDM1A O60341 1/20 0.52
AGTR1 P30556 1/20 0.52
OPRK1 P41145 1/20 0.52
TDP1 Q9NUW8 2/20 0.51
PSMD14 O00487 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL684208 0.90 RAB9A (0.60) RAB9AKMT2AMEN1SMN1; SMN2CA1
SCHEMBL683966 0.89 MAPT (0.58) RAB9AKDM4EKMT2AMEN1LMNA
SCHEMBL684667 0.88 RAB9A (0.50) RAB9AKDM4EKMT2AMEN1LMNA
SCHEMBL684974 0.88 CYP1A2 (0.56) RAB9AKDM4EKMT2AMEN1LMNA
SCHEMBL685042 0.84 MAPT (0.55) RAB9AKDM4EKMT2AMEN1LMNA
SCHEMBL684892 0.83 KDM1A (0.63) RAB9AKMT2AMEN1LMNAHTT
SCHEMBL683983 0.83 RAB9A (0.57) RAB9AKDM4EKMT2AMEN1LMNA
SCHEMBL661128 0.83 RAB9A (0.57) RAB9AKDM4EKMT2AMEN1LMNA
SCHEMBL684011 0.80 NPC1 (0.53) RAB9AKDM4EKMT2AMEN1LMNA
SCHEMBL6571415 0.80 RAB9A (0.76) RAB9AKDM4EKMT2AMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8906829-B2 Synergistic algicidal compositions including hydrazone derivatives and copper DOW AGROSCIENCES LLC (US) 2014-12-09 US disclosed
US-8906829-B2 Synergistic algicidal compositions including hydrazone derivatives and copper DOW AGROSCIENCES LLC (US) 2014-12-09 US disclosed
US-8715745-B2 Fungicidal compositions including hydrazone derivatives and copper DOW AGROSCIENCES, LLC. (US) 2014-05-06 US disclosed
US-8715745-B2 Fungicidal compositions including hydrazone derivatives and copper DOW AGROSCIENCES, LLC. (US) 2014-05-06 US disclosed
US-20120046170-A1 SYNERGISTIC ALGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER DOW AGROSCIENCES LLC (US) 2012-02-23 US disclosed
WO-2012024494-A1 SYNERGISTIC ALGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER DOW AGROSCIENCES LLC (US) 2012-02-23 WO disclosed
US-20120046170-A1 SYNERGISTIC ALGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER DOW AGROSCIENCES LLC (US) 2012-02-23 US disclosed
US-20120010075-A1 SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER DOW AGROSCIENCES LLC (US) 2012-01-12 US disclosed
US-20120010075-A1 SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER DOW AGROSCIENCES LLC (US) 2012-01-12 US disclosed
US-20120009274-A1 FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER DOW AGROSCIENCES LLC (US) 2012-01-12 US disclosed
US-20120009274-A1 FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER DOW AGROSCIENCES LLC (US) 2012-01-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120010075-A1 SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER SOD1, CYP51A1, SOD3 RAB9A 3846/4885KDM4E 1473/4885KMT2A 1362/4885
US-20120009274-A1 FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER SOD1, CYP51A1, CYP4Z1 RAB9A 3616/4885KDM4E 1286/4885KMT2A 1224/4885
US-20120046170-A1 SYNERGISTIC ALGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER ALG1, SOD1, DHPS RAB9A 3936/4885KDM4E 4139/4885KMT2A 2866/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.