Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.59 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.55 |
| ▸ | CDK9 | P50750 | 2/20 | 0.55 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7063425 | 0.87 | ADRA1D (0.47) | DRD2DRD4DRD3 | |
| SCHEMBL7665709 | 0.86 | ADRA1D (0.52) | DRD2CCNT1CDK9 | |
| SCHEMBL6848549 | 0.78 | CCR2 (0.50) | DRD2 | |
| SCHEMBL23595887 | 0.77 | HTR2A (0.62) | DRD2KCNH2DRD3 | |
| SCHEMBL7234672 | 0.77 | DRD2 (0.59) | DRD2DRD4DRD3 | |
| SCHEMBL4853312 | 0.77 | ALDH1A1 (0.54) | CCNT1CDK9 | |
| SCHEMBL6646479 | 0.77 | DRD2 (0.52) | DRD2CCNT1CDK9 | |
| SCHEMBL14619656 | 0.76 | DRD2 (0.60) | DRD2DRD3 | |
| SCHEMBL6848950 | 0.75 | DRD2 (0.55) | DRD2DRD3 | |
| SCHEMBL7662199 | 0.75 | DRD2 (0.54) | DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040242609-A1 | Selective melanin concentrating hormone-1 (MCH1) receptor antagonists and uses thereof | SYNAPTIC PHARMACEUTICAL CORPORATION | 2004-12-02 | — | — | US | disclosed |
| US-20030082623-A1 | DNA encoding a human melanin concentrating hormone receptor (MCH1) and uses thereof | H. LUNDBECK A/S (DK) | 2003-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030082623-A1 | DNA encoding a human melanin concentrating hormone receptor (MCH1) and uses thereof | MCHR1, MCHR2, MC1R | DRD2 271/4885CCNT1 3483/4885CDK9 4252/4885 |
| US-20040242609-A1 | Selective melanin concentrating hormone-1 (MCH1) receptor antagonists and uses thereof | MCHR1, MCHR2, MC4R | DRD2 175/4885CCNT1 3349/4885CDK9 4327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.