SCHEMBL68477

SCHEMBL68477

O=C(c1cccc2ccccc12)P(=O)(c1ccccc1)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A1 P22736 1/20 0.58
NR4A2 P43354 1/20 0.58
NR4A3 Q92570 1/20 0.58
MMP3 P08254 1/20 0.53
HDAC8 Q9BY41 1/20 0.53
CDC25B P30305 1/20 0.51
PLK1 P53350 1/20 0.51
L3MBTL1 Q9Y468 2/20 0.50
PTK2B Q14289 1/20 0.50
DEGS1 O15121 1/20 0.49
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
PTPN1 P18031 1/20 0.47
NR1H4 Q96RI1 1/20 0.47
ALDH1A1 P00352 1/20 0.46
HPGD P15428 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
TDP1 Q9NUW8 2/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30039374 0.86 NR4A1 (0.58) NR4A1NR4A2NR4A3MMP3HDAC8
SCHEMBL17023658 0.82 CA2 (0.48) L3MBTL1NPC1RAB9AALDH1A1HPGD
SCHEMBL4610305 0.81 PTK2B (0.67) NR4A1NR4A2NR4A3MMP3HDAC8
SCHEMBL31484232 0.78 CDC25B (0.51) NR4A1NR4A2NR4A3MMP3HDAC8
SCHEMBL30308102 0.77 L3MBTL1 (0.49) NR4A1NR4A2NR4A3MMP3HDAC8
Naphthoic Acid SCHEMBL31312722 0.76 NR4A1 (0.84) NR4A1NR4A2NR4A3MMP3HDAC8
SCHEMBL28788708 0.75 TERT (0.45) CDC25BNPC1RAB9AALDH1A1HPGD
SCHEMBL4611380 0.75 NR4A1 (0.53) NR4A1NR4A2NR4A3MMP3HDAC8
Naphthoic Acid SCHEMBL17258 0.74 NR4A1 (1.00) NR4A1NR4A2NR4A3MMP3HDAC8
Naphthoic Acid SCHEMBL29352220 0.74 NR4A1 (1.00) NR4A1NR4A2NR4A3MMP3HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3689338-A1 POLYMER FORMULATIONS FOR NASOLACRIMAL STIMULATION Oculeve, Inc. (US) 2020-08-05 EP claimed
EP-3110405-A2 POLYMER FORMULATIONS FOR NASOLACRIMAL STIMULATION Oculeve, Inc. (US) 2017-01-04 EP claimed
WO-2015130707-A2 POLYMER FORMULATIONS FOR NASOLACRIMAL STIMULATION OCULEVE, INC. (US) 2015-09-03 WO claimed
US-20150238754-A1 POLYMER FORMULATIONS FOR NASOLACRIMAL STIMULATION OCULEVE, INC. 2015-08-27 US claimed
CN-115819455-B Acylphosphine oxide compound and preparation method thereof 南方科技大学 2025-03-28 CN disclosed
CN-115819455-A Acyl phosphine oxide compound and preparation method thereof 南方科技大学 2023-03-21 CN disclosed
US-20210069496-A1 POLYMER FORMULATIONS FOR NASOLACRIMAL STIMULATION OCULEVE INC (US) 2021-03-11 US disclosed
US-10799696-B2 Polymer formulations for nasolacrimal stimulation OCULEVE, INC. (US) 2020-10-13 US disclosed
EP-3689338-A1 POLYMER FORMULATIONS FOR NASOLACRIMAL STIMULATION Oculeve, Inc. (US) 2020-08-05 EP disclosed
CN-111298285-A Polymer formulations for nasolacrimal stimulation 奥库利维公司 2020-06-19 CN disclosed
CN-106470673-B Polymer formulations for nasolacrimal stimulation 奥库利维公司 2020-01-31 CN disclosed
US-20180280688-A1 POLYMER FORMULATIONS FOR NASOLACRIMAL STIMULATION OCULEVE, INC. 2018-10-04 US disclosed
US-20080239045-A1 INK SET FOR INKJET RECORDING AND INKJET RECORDING METHOD FUJIFILM CORPORATION (JP) 2008-10-02 US disclosed
US-20080180503-A1 INK SET FOR INKJET RECORDING AND INKJET RECORDING METHOD FUJIFILM CORPORATION (JP) 2008-07-31 US disclosed
US-20080180503-A1 INK SET FOR INKJET RECORDING AND INKJET RECORDING METHOD FUJIFILM CORPORATION (JP) 2008-07-31 US disclosed
US-20080182031-A1 Sensitizing dye, an alpha-aminoketone or acyl phosphine oxide polymerization initiator and an ethylenically unsaturated bond-containing polymerizable compound FUJIFILM CORPORATION (JP) 2008-07-31 US disclosed
US-20080182031-A1 Sensitizing dye, an alpha-aminoketone or acyl phosphine oxide polymerization initiator and an ethylenically unsaturated bond-containing polymerizable compound FUJIFILM CORPORATION (JP) 2008-07-31 US disclosed
US-20070007698-A1 Method of producting three-dimensional model FUJIFILM CORPORATION (JP) 2007-01-11 US disclosed
US-20070007698-A1 Method of producting three-dimensional model FUJIFILM CORPORATION (JP) 2007-01-11 US disclosed
US-20020022130-A1 UV-curable binder composition for magnetic recording media and photoinitiator mixture EMTEC MAGNETICS GMBH (DE) 2002-02-21 US disclosed