Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.49 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGAV | P06756 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.46 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.46 |
| ▸ | PYGL | P06737 | 1/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4308790 | 0.87 | CA2 (0.56) | CA2KMT2AGPR34ADAMTS5MMP2 | |
| SCHEMBL20578232 | 0.85 | CA2 (0.58) | CA2ITGB3ITGAVMME | |
| SCHEMBL3829705 | 0.85 | FOLH1 (0.61) | CA2KMT2AMME | |
| SCHEMBL7275554 | 0.85 | CA2 (0.58) | CA2ITGB3ITGAVMME | |
| SCHEMBL27167053 | 0.85 | CA2 (0.58) | CA2ITGB3ITGAVMME | |
| SCHEMBL5851226 | 0.85 | FOLH1 (0.61) | CA2KMT2AMME | |
| SCHEMBL5490779 | 0.85 | FOLH1 (0.61) | CA2KMT2AMME | |
| SCHEMBL1012053 | 0.84 | MME (0.63) | CA2MME | |
| SCHEMBL1012023 | 0.84 | MME (0.63) | CA2MME | |
| SCHEMBL1012022 | 0.84 | MME (0.63) | CA2MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6800464-B2 | FOR PREPARATION OF D-AMINO ACIDS STARTING FROM 5'-SUBSTITUTED HYDANTOINS | DEGUSSA AG (DE) | 2004-10-05 | — | — | US | disclosed |