Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.85 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.85 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.85 |
| ▸ | RAB9A | P51151 | 7/20 | 0.70 |
| ▸ | NPC1 | O15118 | 6/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.70 |
| ▸ | MAPT | P10636 | 5/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | KDM1A | O60341 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | APAF1 | O14727 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12218408 | 0.92 | CYP1A2 (1.00) | CYP1A2CYP3A4CYP2C19RAB9ANPC1 | |
| SCHEMBL685019 | 0.88 | CYP1A2 (0.66) | CYP1A2CYP3A4CYP2C19RAB9ANPC1 | |
| SCHEMBL684205 | 0.88 | CYP1A2 (0.81) | CYP1A2CYP3A4CYP2C19RAB9ANPC1 | |
| SCHEMBL684652 | 0.87 | KDM1A (0.70) | CYP1A2CYP3A4CYP2C19RAB9ANPC1 | |
| SCHEMBL683982 | 0.86 | CYP1A2 (0.63) | CYP1A2CYP3A4CYP2C19RAB9ANPC1 | |
| SCHEMBL684571 | 0.85 | CYP1A2 (0.61) | CYP1A2CYP3A4CYP2C19RAB9ANPC1 | |
| SCHEMBL683996 | 0.82 | RAB9A (0.81) | CYP1A2CYP3A4CYP2C19RAB9ANPC1 | |
| SCHEMBL683983 | 0.82 | RAB9A (0.57) | CYP1A2CYP3A4CYP2C19RAB9ANPC1 | |
| SCHEMBL661128 | 0.82 | RAB9A (0.57) | CYP1A2CYP3A4CYP2C19RAB9ANPC1 | |
| SCHEMBL684970 | 0.81 | DUSP3 (0.70) | CYP1A2CYP3A4CYP2C19RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8906829-B2 | Synergistic algicidal compositions including hydrazone derivatives and copper | DOW AGROSCIENCES LLC (US) | 2014-12-09 | — | — | US | disclosed |
| US-8906829-B2 | Synergistic algicidal compositions including hydrazone derivatives and copper | DOW AGROSCIENCES LLC (US) | 2014-12-09 | — | — | US | disclosed |
| US-8715745-B2 | Fungicidal compositions including hydrazone derivatives and copper | DOW AGROSCIENCES, LLC. (US) | 2014-05-06 | — | — | US | disclosed |
| US-8715745-B2 | Fungicidal compositions including hydrazone derivatives and copper | DOW AGROSCIENCES, LLC. (US) | 2014-05-06 | — | — | US | disclosed |
| US-20120046170-A1 | SYNERGISTIC ALGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-02-23 | — | — | US | disclosed |
| WO-2012024494-A1 | SYNERGISTIC ALGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-02-23 | — | — | WO | disclosed |
| US-20120046170-A1 | SYNERGISTIC ALGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-02-23 | — | — | US | disclosed |
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-01-12 | — | — | US | disclosed |
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-01-12 | — | — | US | disclosed |
| US-20120009274-A1 | FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-01-12 | — | — | US | disclosed |
| US-20120009274-A1 | FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | SOD1, CYP51A1, SOD3 | CYP1A2 11/4885CYP3A4 48/4885CYP2C19 138/4885 |
| US-20120009274-A1 | FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | SOD1, CYP51A1, CYP4Z1 | CYP1A2 12/4885CYP3A4 71/4885CYP2C19 120/4885 |
| US-20120046170-A1 | SYNERGISTIC ALGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | ALG1, SOD1, DHPS | CYP1A2 1110/4885CYP3A4 2091/4885CYP2C19 2087/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.