Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.73 |
| ▸ | MAPT | P10636 | 2/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.73 |
| ▸ | NPC1 | O15118 | 2/20 | 0.73 |
| ▸ | JUN | P05412 | 1/20 | 0.73 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.73 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | APAF1 | O14727 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.63 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | CYP1A1 | P04798 | 10/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 10/20 | 0.57 |
| ▸ | CYP1B1 | Q16678 | 10/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6848209 | 1.00 | RAB9A (0.73) | RAB9AMAPTKDM4ENPC1JUN | |
| SCHEMBL30949406 | 0.86 | MAPT (0.60) | RAB9AMAPTKDM4ENPC1JUN | |
| SCHEMBL5598850 | 0.85 | MAPT (1.00) | RAB9AMAPTKDM4ENPC1JUN | |
| SCHEMBL5598852 | 0.85 | MAPT (1.00) | RAB9AMAPTKDM4ENPC1JUN | |
| SCHEMBL334615 | 0.83 | RAB9A (0.76) | RAB9AMAPTKDM4ENPC1JUN | |
| SCHEMBL334614 | 0.83 | RAB9A (0.76) | RAB9AMAPTKDM4ENPC1JUN | |
| Hydrochloric Acid SCHEMBL11971079 | 0.83 | MAPT (0.96) | RAB9AMAPTKDM4ENPC1JUN | |
| SCHEMBL29416684 | 0.83 | RAB9A (0.76) | RAB9AMAPTKDM4ENPC1JUN | |
| SCHEMBL755249 | 0.83 | RAB9A (0.76) | RAB9AMAPTKDM4ENPC1JUN | |
| Hydrochloric Acid SCHEMBL11971085 | 0.83 | MAPT (0.96) | RAB9AMAPTKDM4ENPC1JUN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5214151-A | Method for the preparation of α, β-unsaturated ketones | NIPPON SODA CO., LTD. (JP) | 1993-05-25 | — | — | US | claimed |
| US-4514267-A | Zinc electroplating additive concentrate | OMI INTERNATIONAL CORPORATION (US) | 1985-04-30 | — | — | US | claimed |
| WO-2021158869-A1 | COMPOUNDS, COMPOSITIONS, METHODS FOR TREATING DISEASES AND NERVE DAMAGE, AND METHODS FOR PREPARING COMPOUNDS | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2021-08-12 | — | — | WO | disclosed |
| WO-2021058018-A1 | INHIBITORS OF KRAS G12C | BEIGENE, LTD. (KY) | 2021-04-01 | — | — | WO | disclosed |
| US-20160296592-A1 | Methods and Compositions for the Treatment of Proteinuric Diseases | THE GENERAL HOSPITAL CORPORATION | 2016-10-13 | — | — | US | disclosed |
| US-9345739-B2 | Methods and compositions for the treatment of proteinuric diseases | THE GENERAL HOSPITAL CORPORATION (US) | 2016-05-24 | — | — | US | disclosed |
| US-8486370-B2 | Heterocyclic ligands for integrin imaging and therapy | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-07-16 | — | — | US | disclosed |
| US-20120053170-A1 | NICOTINAMIDE DERIVATIVES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF AS ANTICANCER DRUGS | SANOFI (FR) | 2012-03-01 | — | — | US | disclosed |
| US-20100297139-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PROTEINURIC DISEASES | THE GENERAL HOSPITAL CORPORATION | 2010-11-25 | — | — | US | disclosed |
| US-20100256355-A1 | OXAZOLIDINONE DERIVATIVE HAVING 7-MEMBERED HETERO RING | Research Foundation ITSUU Laboratory and Shionogi & Co., Ltd. | 2010-10-07 | — | — | US | disclosed |
| US-7622487-B2 | Piperidine derivative, process for producing the same, and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-24 | — | — | US | disclosed |
| US-20020103203-A1 | Amide compounds and pharmaceutical compositions for inhibiting protein kinases, and methods for their use | AGOURON PHARMACEUTICALS, INC. | 2002-08-01 | — | — | US | disclosed |
| WO-2001053274-A1 | AMIDE COMPOUNDS FOR INHIBITING PROTEIN KINASES | AGOURON PHARMACEUTICALS, INC. (US) | 2001-07-26 | — | — | WO | disclosed |
| US-5214151-A | Method for the preparation of α, β-unsaturated ketones | NIPPON SODA CO., LTD. (JP) | 1993-05-25 | — | — | US | disclosed |
| EP-0104876-B1 | HERBICIDAL CYCLOHEXANE-1,3-DIONE DERIVATIVES | ICI AUSTRALIA LIMITED (AU) | 1991-12-27 | — | — | EP | disclosed |
| EP-0457912-A1 | METHOD FOR THE PREPARATION OF $g(a),$g(b)-UNSATURATED KETONES | NIPPON SODA CO., LTD. (JP) | 1991-11-27 | — | — | EP | disclosed |
| WO-1991007371-A1 | METHOD FOR THE PREPARATION OF α,β-UNSATURATED KETONES | NIPPON SODA CO., LTD. (JP) | 1991-05-30 | — | — | WO | disclosed |
| US-4631081-A | Herbicidal cyclohexane-1,3-dione derivatives | ICI AUSTRALIA LIMITED (AU) | 1986-12-23 | — | — | US | disclosed |
| US-4514267-A | Zinc electroplating additive concentrate | OMI INTERNATIONAL CORPORATION (US) | 1985-04-30 | — | — | US | disclosed |
| EP-0104876-A2 | Herbicidal cyclohexane-1,3-dione derivatives | ICI AUSTRALIA LIMITED (AU) | 1984-04-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160296592-A1 | Methods and Compositions for the Treatment of Proteinuric Diseases | ITGB3, PLAUR, PROC | RAB9A 783/4885MAPT 2454/4885KDM4E 4380/4885 |
| US-20100297139-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PROTEINURIC DISEASES | ITGB3, PLAUR, PROC | RAB9A 783/4885MAPT 2454/4885KDM4E 4380/4885 |
| US-20120053170-A1 | NICOTINAMIDE DERIVATIVES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF AS ANTICANCER DRUGS | NAMPT, NNT, NQO1 | RAB9A 1557/4885MAPT 2480/4885KDM4E 1950/4885 |
| US-20020103203-A1 | Amide compounds and pharmaceutical compositions for inhibiting protein kinases, and methods for their use | BRAF, CNKSR1, UACA | RAB9A 1183/4885MAPT 899/4885KDM4E 1227/4885 |
| US-20100256355-A1 | OXAZOLIDINONE DERIVATIVE HAVING 7-MEMBERED HETERO RING | NR0B2, NR0B1, NR2C2 | RAB9A 4701/4885MAPT 4696/4885KDM4E 3762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.