Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.58 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.58 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.58 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11295545 | 0.87 | PTGS2 (0.56) | PTGS2PTGS1AKR1B1CXCL8GLO1 | |
| SCHEMBL2237110 | 0.83 | PTGS2 (0.61) | PTGS2PTGS1AKR1B1CXCL8GLO1 | |
| SCHEMBL4885665 | 0.82 | PTGS2 (0.47) | PTGS2PTGS1AKR1B1CXCL8GLO1 | |
| SCHEMBL11364366 | 0.80 | PTGS1 (0.46) | PTGS2PTGS1AKR1B1CXCL8GLO1 | |
| SCHEMBL31445978 | 0.79 | PTGS2 (0.46) | PTGS2PTGS1AKR1B1CXCL8GLO1 | |
| SCHEMBL11380056 | 0.79 | PTGS1 (0.45) | PTGS2PTGS1AKR1B1CXCL8GLO1 | |
| SCHEMBL2235453 | 0.79 | PTGS2 (0.56) | PTGS2PTGS1AKR1B1CXCL8GLO1 | |
| SCHEMBL3974235 | 0.78 | CXCL8 (0.59) | PTGS2PTGS1AKR1B1CXCL8GLO1 | |
| SCHEMBL2237360 | 0.78 | PTGS2 (0.77) | PTGS2PTGS1AKR1B1CXCL8GLO1 | |
| SCHEMBL11438082 | 0.76 | PCSK9 (0.51) | PTGS2PTGS1AKR1B1CXCL8GLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2479203-A1 | AROMATIC POLYESTER | Muroran Institute of Technology (JP) | 2012-07-25 | — | — | EP | disclosed |
| US-20120172570-A1 | AROMATIC POLYESTER | NITTA CORPORATION | 2012-07-05 | — | — | US | disclosed |
| US-8129493-B2 | Aromatic polyester | MURORAN INSTITUTE OF TECHNOLOGY (JP) | 2012-03-06 | — | — | US | disclosed |
| US-20110224343-A1 | MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME | MURORAN INSTITUTE OF TECHNOLOGY (JP) | 2011-09-15 | — | — | US | disclosed |
| US-20110092662-A1 | AROMATIC POLYESTER | NITTA CORPORATION (JP) | 2011-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110224343-A1 | MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME | F12, PHAX, WDR82 | PTGS2 2866/4885PTGS1 2544/4885AKR1B1 1027/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.