Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.47 |
| ▸ | ESRRG | P62508 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.43 |
| ▸ | ADCYAP1R1 | P41586 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL684731 | 0.90 | CYP3A4 (0.60) | CYP3A4GAACYP2D6CYP2C19SMN1; SMN2 | |
| SCHEMBL684898 | 0.87 | SMN1; SMN2 (0.51) | CYP3A4GAACYP2D6CYP2C19SMN1; SMN2 | |
| SCHEMBL684902 | 0.86 | MAPT (0.53) | MTORCYP3A4GAACYP2D6CYP2C19 | |
| SCHEMBL684083 | 0.86 | MAPT (0.52) | CYP3A4GAACYP2D6CYP2C19SMN1; SMN2 | |
| SCHEMBL685077 | 0.86 | SMN1; SMN2 (0.52) | CYP3A4GAACYP2D6CYP2C19SMN1; SMN2 | |
| SCHEMBL684021 | 0.82 | MAPT (0.56) | MTORCYP3A4GAASMN1; SMN2MAPK1 | |
| SCHEMBL685163 | 0.80 | MAPT (0.61) | MTORCYP3A4GAACYP2D6CYP2C19 | |
| SCHEMBL684901 | 0.79 | RAB9A (0.50) | CYP3A4GAACYP2D6CYP2C19SMN1; SMN2 | |
| SCHEMBL685376 | 0.78 | SMN1; SMN2 (0.57) | CYP3A4GAASMN1; SMN2USP2MAPK1 | |
| SCHEMBL14459823 | 0.78 | LMNA (0.55) | MAPTADCYAP1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8476194-B2 | Fungicidal compositions including hydrazone derivatives and copper | DOW AGROSCIENCES, LLC (US) | 2013-07-02 | — | — | US | disclosed |
| US-8476194-B2 | Fungicidal compositions including hydrazone derivatives and copper | DOW AGROSCIENCES, LLC (US) | 2013-07-02 | — | — | US | disclosed |
| US-20120021066-A1 | FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-01-26 | — | — | US | disclosed |
| US-20120021066-A1 | FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-01-26 | — | — | US | disclosed |
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | SOD1, CYP51A1, SOD3 | MTOR 2134/4885CYP3A4 48/4885GAA 670/4885 |
| US-20120021066-A1 | FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | SOD1, CYP51A1, CYP4Z1 | MTOR 2360/4885CYP3A4 71/4885GAA 386/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.