Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASF1A | Q9Y294 | 2/20 | 0.74 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.73 |
| ▸ | MAPT | P10636 | 6/20 | 0.73 |
| ▸ | RAB9A | P51151 | 5/20 | 0.73 |
| ▸ | MEN1 | O00255 | 5/20 | 0.73 |
| ▸ | MITF | O75030 | 4/20 | 0.73 |
| ▸ | NPC1 | O15118 | 3/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.73 |
| ▸ | KLF5 | Q13887 | 2/20 | 0.72 |
| ▸ | HTT | P42858 | 5/20 | 0.69 |
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.69 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.69 |
| ▸ | MMP2 | P08253 | 1/20 | 0.69 |
| ▸ | BLM | P54132 | 1/20 | 0.69 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26974369 | 0.92 | RAB9A (0.73) | ASF1APIK3CGKMT2AKDM4EMAPT | |
| SCHEMBL685183 | 0.90 | PIK3CG (0.70) | ASF1APIK3CGKMT2AKDM4EMAPT | |
| SCHEMBL19283338 | 0.89 | KMT2A (0.76) | ASF1APIK3CGKMT2AKDM4EMAPT | |
| SCHEMBL19283336 | 0.89 | KMT2A (0.76) | ASF1APIK3CGKMT2AKDM4EMAPT | |
| SCHEMBL685060 | 0.89 | MAPT (0.72) | ASF1APIK3CGKMT2AKDM4EMAPT | |
| SCHEMBL30122159 | 0.87 | KMT2A (0.85) | ASF1APIK3CGKMT2AKDM4EMAPT | |
| SCHEMBL684525 | 0.87 | KMT2A (0.85) | ASF1APIK3CGKMT2AKDM4EMAPT | |
| SCHEMBL20446303 | 0.87 | KMT2A (0.85) | ASF1APIK3CGKMT2AKDM4EMAPT | |
| SCHEMBL684930 | 0.86 | KMT2A (0.76) | ASF1APIK3CGKMT2AKDM4EMAPT | |
| SCHEMBL20587552 | 0.85 | KMT2A (0.74) | ASF1APIK3CGKMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11858880-B2 | Anti-fungals compounds targeting the synthesis of fungal sphingolipids | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2024-01-02 | — | — | US | disclosed |
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-01-12 | — | — | US | disclosed |
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | SOD1, CYP51A1, SOD3 | ASF1A 1869/4885PIK3CG 2876/4885KMT2A 1362/4885 |
| US-11858880-B2 | Anti-fungals compounds targeting the synthesis of fungal sphingolipids | ERG28, UGCG, DPM1 | ASF1A 2765/4885PIK3CG 488/4885KMT2A 3071/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.