Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.72 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.65 |
| ▸ | KDM1A | O60341 | 3/20 | 0.63 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 6/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.60 |
| ▸ | MMP2 | P08253 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | ALPL | P05186 | 1/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | ALPI | P09923 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL684807 | 0.93 | MAPT (0.64) | MAPTSIRT1KDM1APIK3CGRAB9A | |
| SCHEMBL26974369 | 0.92 | RAB9A (0.73) | MAPTSIRT1KDM1APIK3CGRAB9A | |
| SCHEMBL685064 | 0.92 | KDM1A (0.72) | MAPTSIRT1KDM1APIK3CGRAB9A | |
| SCHEMBL12387736 | 0.92 | GCGR (0.62) | MAPTSIRT1KDM1APIK3CGRAB9A | |
| SCHEMBL684973 | 0.92 | PIK3CG (0.62) | MAPTKDM1APIK3CGRAB9AKDM4E | |
| SCHEMBL6569747 | 0.92 | PIK3CG (0.62) | MAPTKDM1APIK3CGRAB9AKDM4E | |
| SCHEMBL6569744 | 0.92 | PIK3CG (0.62) | MAPTKDM1APIK3CGRAB9AKDM4E | |
| SCHEMBL684527 | 0.89 | KDM1A (0.81) | MAPTSIRT1KDM1APIK3CGRAB9A | |
| SCHEMBL684944 | 0.89 | ASF1A (0.74) | MAPTSIRT1KDM1APIK3CGRAB9A | |
| SCHEMBL19965934 | 0.89 | L3MBTL1 (0.73) | MAPTRAB9AMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11858880-B2 | Anti-fungals compounds targeting the synthesis of fungal sphingolipids | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2024-01-02 | — | — | US | disclosed |
| US-20120148682-A1 | FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-06-14 | — | — | US | disclosed |
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | SOD1, CYP51A1, SOD3 | MAPT 1491/4885SIRT1 2400/4885KDM1A 484/4885 |
| US-20120148682-A1 | FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | SOD1, CYP51A1, CYP4Z1 | MAPT 921/4885SIRT1 1977/4885KDM1A 291/4885 |
| US-11858880-B2 | Anti-fungals compounds targeting the synthesis of fungal sphingolipids | ERG28, UGCG, DPM1 | MAPT 2146/4885SIRT1 2412/4885KDM1A 2352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.