SCHEMBL6849830

SCHEMBL6849830

N#Cc1c(C#N)c(CC2CCCCC2)c(CC2CCCCC2)c(CC2CCCCC2)c1CC1CCCCC1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCNA2 P20248 1/20 0.39
CDK2 P24941 1/20 0.39
CCNA1 P78396 1/20 0.39
CTSK P43235 2/20 0.36
CTSL P07711 2/20 0.36
CTSB P07858 2/20 0.36
MEN1 O00255 2/20 0.36
ALDH1A1 P00352 2/20 0.36
MAPT P10636 2/20 0.36
KMT2A Q03164 2/20 0.36
KDM4E B2RXH2 1/20 0.36
USP2 O75604 1/20 0.36
LMNA P02545 1/20 0.36
HPGD P15428 1/20 0.36
ALOX15 P16050 1/20 0.36
ALOX12 P18054 1/20 0.36
BRCA1 P38398 1/20 0.36
HTT P42858 1/20 0.36
RECQL P46063 1/20 0.36
HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6849819 0.67 CDK2 (0.51) CCNA2CDK2CCNA1CTSKCTSL
SCHEMBL14367116 0.65 MAOA (0.49) ALDH1A1CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL17325048 0.62 NOS3 (0.32) HTR3AHRH4DAOCYP1A2
SCHEMBL1524762 0.61 HTR3A (0.39) KMT2ARECQLHTR3AHRH4DAO
SCHEMBL20491422 0.61 CTSK (0.39) CCNA2CDK2CCNA1CTSKCTSL
SCHEMBL2334878 0.61 HTR3A (0.39) KMT2ARECQLHTR3AHRH4DAO
SCHEMBL13744804 0.61 CTSK (0.39) CCNA2CDK2CCNA1CTSKCTSL
SCHEMBL15552104 0.61 HTR3A (0.39) KMT2ARECQLHTR3AHRH4DAO
SCHEMBL91247 0.61
SCHEMBL8094847 0.61 CTSK (0.39) CCNA2CDK2CCNA1CTSKCTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004106436-A1 PHTHALOCYANINE COMPOUNDS YORK UNIVERSITY (CA) 2004-12-09 WO claimed