Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.50 |
| ▸ | CCR5 | P51681 | 2/20 | 0.50 |
| ▸ | CCR8 | P51685 | 2/20 | 0.50 |
| ▸ | KDM5C | P41229 | 7/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | KDM2A | Q9Y2K7 | 5/20 | 0.42 |
| ▸ | KDM3A | Q9Y4C1 | 5/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.42 |
| ▸ | KDM6B | O15054 | 4/20 | 0.42 |
| ▸ | KDM4A | O75164 | 6/20 | 0.41 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.38 |
| ▸ | KDM4B | O94953 | 3/20 | 0.38 |
| ▸ | JMJD6 | Q6NYC1 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TET3 | O43151 | 1/20 | 0.34 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | ASPH | Q12797 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2637576 | 0.98 | CCR1 (0.52) | CCR1CCR5CCR8KDM5CKDM4E | |
| SCHEMBL17669635 | 0.84 | CCR1 (0.55) | CCR1CCR5CCR8KDM5CKDM4E | |
| SCHEMBL246279 | 0.80 | LOXL2 (0.36) | CCR1CCR5CCR8KDM5CKDM4E | |
| SCHEMBL2927955 | 0.78 | FFAR1 (0.38) | KDM5CKDM4EKDM2AKDM3AKDM4C | |
| SCHEMBL2921165 | 0.78 | ALDH1A1 (0.40) | KDM5CKDM4EKDM2AKDM3AKDM4C | |
| SCHEMBL9319785 | 0.78 | RECQL (0.41) | KDM5CKDM4EKDM2AKDM3AKDM4C | |
| Water SCHEMBL8053672 | 0.78 | LOXL2 (0.36) | CCR1CCR5CCR8KDM5CKDM4E | |
| SCHEMBL7447847 | 0.78 | NOS3 (0.55) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL6846318 | 0.78 | CCR1 (0.48) | CCR1CCR5CCR8KDM5CKDM4E | |
| SCHEMBL14846471 | 0.78 | KDM4C (0.60) | KDM5CKDM4EKDM2AKDM3AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968507-B1 | PHOTOVOLTAIC CELL | COVION ORGANIC SEMICONDUCTORS (DE) | 2004-12-15 | — | — | EP | disclosed |