Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRG | P62508 | 1/20 | 0.53 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.51 |
| ▸ | PPID | Q08752 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 4/20 | 0.49 |
| ▸ | CA2 | P00918 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6415918 | 0.85 | CA1 (0.66) | ESRRGST14PPIDHIF1ACA1 | |
| SCHEMBL22403771 | 0.85 | HPGD (0.54) | ESRRGST14PPIDCA1CA2 | |
| SCHEMBL6415914 | 0.84 | ST14 (0.54) | ESRRGST14PPIDHIF1ACA1 | |
| SCHEMBL19334528 | 0.84 | ACACB (0.56) | ESRRGST14PPIDCA1CA2 | |
| SCHEMBL5574769 | 0.83 | LMNA (0.66) | CA1CA2LMNACA9CA12 | |
| SCHEMBL7753239 | 0.83 | TPSAB1 (0.53) | PPIDCA1CA2LMNAHPGD | |
| SCHEMBL2191045 | 0.83 | KDM4E (0.65) | ESRRGLMNAGFER | |
| SCHEMBL15940162 | 0.82 | ESRRG (0.57) | ESRRGST14PPIDHIF1ACA1 | |
| SCHEMBL6413637 | 0.82 | CA1 (0.55) | ESRRGPPIDCA1CA2CA9 | |
| SCHEMBL20052590 | 0.81 | LMNA (0.47) | ST14CA1CA2LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2289882-A1 | 3-oxopiperazinium derivatives as agonists of nerve growth factor and their use as medicaments | Institut d'Investigacions Biomédiques August PI I Sunyer (ES) | 2011-03-02 | — | — | EP | disclosed |