Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 5/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | PPID | Q08752 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PPIB | P23284 | 1/20 | 0.46 |
| ▸ | PPIA | P62937 | 1/20 | 0.46 |
| ▸ | PPIG | Q13427 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22852533 | 0.85 | TPSAB1 (0.58) | TPSAB1EPHX2PPIDALDH1A1HTT | |
| SCHEMBL9798143 | 0.84 | ALDH1A1 (0.58) | TPSAB1EPHX2MAPK1ALDH1A1HTT | |
| SCHEMBL6850677 | 0.83 | ESRRG (0.53) | PPIDALDH1A1CA1CA2LMNA | |
| SCHEMBL21781874 | 0.82 | CA1 (0.64) | TPSAB1EPHX2PPIDEPHX1CYP2C9 | |
| SCHEMBL18868428 | 0.82 | ALDH1A1 (0.61) | TPSAB1ALDH1A1MAPTRAB9AMEN1 | |
| SCHEMBL4035227 | 0.82 | KMT2A (0.68) | ALDH1A1SMN1; SMN2CYP2C9CYP2C19POLB | |
| SCHEMBL3517253 | 0.81 | TPSAB1 (0.53) | TPSAB1EPHX2PPIDHTTEPHX1 | |
| SCHEMBL22500066 | 0.81 | L3MBTL1 (0.62) | TPSAB1MAPK1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL15651444 | 0.81 | PPID (0.54) | TPSAB1EPHX2PPIDALDH1A1EPHX1 | |
| SCHEMBL11731507 | 0.81 | KMT2A (0.65) | ALDH1A1SMN1; SMN2POLBRAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592356-B2 | Triazoles as farnesyl transferase inhibitors | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-09-22 | — | — | US | disclosed |
| US-20080103150-A1 | Triazoles as Farnesyl Transferase Inhibitors | SAHA ASHIS K | 2008-05-01 | — | — | US | disclosed |
| EP-1068390-A1 | METHOD FOR IMPROVED WET STRENGTH PAPER | Kimberly-Clark Worldwide, Inc. (US) | 2001-01-17 | — | — | EP | disclosed |
| WO-1999045201-A1 | METHOD FOR IMPROVED WET STRENGTH PAPER | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 1999-09-10 | — | — | WO | disclosed |
| US-5935383-A | Method for improved wet strength paper | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 1999-08-10 | — | — | US | disclosed |
| US-4141890-A | FIBER-REACTIVE | CIBA-GEIGY CORPORATION (US) | 1979-02-27 | — | — | US | disclosed |
| US-4067864-A | FOR CELLULOSE OR POLYAMIDES | CIBA-GEIGY AG (CH) | 1978-01-10 | — | — | US | disclosed |
| US-4039523-A | YELLOW | CIBA-GEIGY AG (CH) | 1977-08-02 | — | — | US | disclosed |
| US-4017477-A | 3-Halogeno-6-hydroxy-pyridone-(2) azo dyestuffs | CIBA-GEIGY AG (CH) | 1977-04-12 | — | — | US | disclosed |
| US-4001203-A | Heavy metal complexes of azo dyestuffs containing a heterocyclic diazo component and the residue of 5-halogeno-2,3-dihydrozypyridine as coupling component | CIBA-GEIGY AG (CH) | 1977-01-04 | — | — | US | disclosed |
| US-3971738-A | Heavy metal complexes of azo compounds containing a halogeno-2,3-dihydroxy pyridine coupling component | CIBA-GEIGY AG (CH) | 1976-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080103150-A1 | Triazoles as Farnesyl Transferase Inhibitors | CYP7A1, HSD3B1, CES1 | TPSAB1 423/4885EPHX2 352/4885PPID 4392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.