Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN5 | P54829 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6851099 | 0.75 | PTPN1 (0.31) | ALDH1A1HPGDBCL2L1HSD17B10 | |
| SCHEMBL4336208 | 0.75 | ALDH1A1 (0.34) | ALDH1A1HPGDBCL2L1HSD17B10 | |
| SCHEMBL28418518 | 0.71 | POLB (0.33) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL6851030 | 0.69 | CA2 (0.33) | — | |
| SCHEMBL6852957 | 0.66 | ALDH1A1 (0.31) | ALDH1A1HPGDBCL2L1HSD17B10 | |
| SCHEMBL28106479 | 0.66 | KDM4E (0.33) | ALDH1A1HPGDBCL2L1HSD17B10 | |
| Phosphoric Acid SCHEMBL31187365 | 0.64 | ALDH1A1 (0.52) | PTPN5ALDH1A1HPGDBCL2L1HSD17B10 | |
| SCHEMBL11074497 | 0.62 | ALDH1A1 (0.41) | ALDH1A1HPGDBCL2L1HSD17B10 | |
| SCHEMBL7551777 | 0.61 | ALDH1A1 (0.33) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL28856005 | 0.61 | HSD17B10 (0.40) | ALDH1A1HPGDBCL2L1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294378-A4 | THROMBOPOIETIN MIMETICS | SMITHKLINE BEECHAM CORP (US) | 2004-01-28 | — | — | EP | disclosed |
| EP-1294378-A2 | THROMBOPOIETIN MIMETICS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-03-26 | — | — | EP | disclosed |
| WO-2001089457-A2 | THROMBOPOIETIN MIMETICS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-11-29 | — | — | WO | disclosed |