SCHEMBL685084

SCHEMBL685084

COc1ccc(/C(C)=N/NC(=O)c2ccccc2O)c(O)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.62
CYP3A4 P08684 2/20 0.62
LMNA P02545 2/20 0.62
CYP1A2 P05177 1/20 0.62
PGR P06401 1/20 0.62
ADORA3 P0DMS8 1/20 0.62
AR P10275 1/20 0.62
CHRM1 P11229 1/20 0.62
ALOX15 P16050 1/20 0.62
TBXA2R P21731 1/20 0.62
SLC6A2 P23975 1/20 0.62
CYP2C19 P33261 1/20 0.62
ADRA1A P35348 1/20 0.62
HIF1A Q16665 1/20 0.62
KDM1A O60341 1/20 0.60
RAB9A P51151 7/20 0.58
SMN1; SMN2 Q16637 7/20 0.58
KDM4E B2RXH2 5/20 0.58
NPC1 O15118 5/20 0.58
GAA P10253 5/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL684680 0.90 RAB9A (0.56) HPGDCYP3A4LMNACYP1A2PGR
SCHEMBL23719209 0.90 RAB9A (0.68) HPGDCYP3A4LMNACYP1A2PGR
SCHEMBL683879 0.89 MAPT (0.65) HPGDCYP3A4LMNACYP1A2PGR
SCHEMBL685049 0.89 RAB9A (0.55) HPGDCYP3A4LMNACYP1A2PGR
SCHEMBL684675 0.87 L3MBTL1 (0.63) HPGDCYP3A4LMNACYP1A2PGR
SCHEMBL1164807 0.87 KDM1A (0.70) HPGDLMNAKDM1ARAB9ASMN1; SMN2
SCHEMBL1164808 0.87 KDM1A (0.70) HPGDLMNAKDM1ARAB9ASMN1; SMN2
SCHEMBL684855 0.85 KDM1A (0.74) HPGDLMNAKDM1ARAB9ASMN1; SMN2
SCHEMBL23701490 0.85 KDM1A (0.74) HPGDLMNAKDM1ARAB9ASMN1; SMN2
SCHEMBL685326 0.84 MAPT (0.61) HPGDCYP3A4CYP1A2KDM1ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120010075-A1 SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER DOW AGROSCIENCES LLC (US) 2012-01-12 US disclosed
US-20120010075-A1 SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER DOW AGROSCIENCES LLC (US) 2012-01-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120010075-A1 SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER SOD1, CYP51A1, SOD3 HPGD 481/4885CYP3A4 48/4885LMNA 4808/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.