Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 4/20 | 0.39 |
| ▸ | CTSS | P25774 | 3/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 2/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6771072 | 0.92 | ALDH1A1 (0.59) | ALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL6765253 | 0.88 | CTSS (0.42) | ALDH1A1KMT2ASIGMAR1ANO1CTSL | |
| SCHEMBL6762509 | 0.85 | S1PR5 (0.44) | ALDH1A1KMT2ASIGMAR1AKR1B1 | |
| SCHEMBL6762505 | 0.84 | CTSL (0.41) | ALDH1A1KMT2ASIGMAR1ANO1NPC1 | |
| SCHEMBL6762138 | 0.81 | ALDH1A1 (0.49) | ALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL6764649 | 0.80 | KMT2A (0.46) | KMT2ASIGMAR1ANO1 | |
| SCHEMBL6762566 | 0.80 | ALDH1A1 (0.49) | ALDH1A1KMT2ASIGMAR1DRD1AKR1B1 | |
| SCHEMBL6771158 | 0.79 | ALOX15 (0.40) | ALDH1A1NPC1CTSLCTSSCTSK | |
| SCHEMBL6765402 | 0.79 | ALDH1A1 (0.47) | ALDH1A1KMT2A | |
| SCHEMBL6765259 | 0.78 | ALDH1A1 (0.47) | ALDH1A1KMT2ASIGMAR1DRD1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774133-B2 | Substituted spiroheterocyclic 1H-3-aryl-pyrrolidine-2,4-dione derivatives, processes for their preparation, and their use as pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 2004-08-10 | — | — | US | disclosed |
| US-6555567-B1 | 2-oxo-3-aryl-4-hydroxy-1-aza-8-thiaspiro(4.5)decane derivatives of given formula; use as arthropodicide or nematicide | BAYER AKTIENGESELLSCHAFT (DE) | 2003-04-29 | — | — | US | disclosed |
| US-6479489-B1 | AN ARTHROPODICIDAL OR NEMATICIDAL COMPOSITION | BAYER AKTIENGESELLSCHAFT (DE) | 2002-11-12 | — | — | US | disclosed |
| US-5981567-A | ARTHROPODICIDAL OR NEMATICIDAL COMPOSITION | BAYER AKTIENGESELLSCHAFT (DE) | 1999-11-09 | — | — | US | disclosed |