Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 8/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ANO1 | Q5XXA6 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | UGCG | Q16739 | 1/20 | 0.42 |
| ▸ | ERCC1 | P07992 | 2/20 | 0.40 |
| ▸ | ERCC4 | Q92889 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6765934 | 0.89 | KMT2A (0.44) | KMT2AP2RX7SIGMAR1ANO1ERCC1 | |
| SCHEMBL849486 | 0.88 | EPHX2 (0.46) | KMT2AP2RX7SIGMAR1ANO1ERCC1 | |
| SCHEMBL10164756 | 0.86 | KMT2A (0.42) | KMT2AP2RX7SIGMAR1ANO1 | |
| SCHEMBL6766386 | 0.86 | SIGMAR1 (0.44) | KMT2AP2RX7SIGMAR1ANO1ERCC1 | |
| SCHEMBL6766382 | 0.85 | KMT2A (0.41) | KMT2AP2RX7SIGMAR1ANO1ERCC1 | |
| SCHEMBL13938980 | 0.84 | ANO1 (0.43) | KMT2AP2RX7ANO1ERCC1ERCC4 | |
| SCHEMBL13385942 | 0.84 | ALDH1A1 (0.48) | KMT2AANO1 | |
| SCHEMBL6771370 | 0.81 | SHMT1 (0.50) | KMT2AP2RX7SIGMAR1POLBCYP3A4 | |
| SCHEMBL6764658 | 0.81 | MEN1 (0.42) | KMT2AP2RX7 | |
| SCHEMBL6850941 | 0.80 | ALDH1A1 (0.47) | KMT2ASIGMAR1ANO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774133-B2 | Substituted spiroheterocyclic 1H-3-aryl-pyrrolidine-2,4-dione derivatives, processes for their preparation, and their use as pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 2004-08-10 | — | — | US | disclosed |
| US-20040009999-A1 | Substituted spiroheterocyclic 1H-3-aryl-pyrrolidine-2,4-dione derivatives, processes for their preparation, and their use as pesticides | FISCHER REINER (DE) | 2004-01-15 | — | — | US | disclosed |
| US-6555567-B1 | 2-oxo-3-aryl-4-hydroxy-1-aza-8-thiaspiro(4.5)decane derivatives of given formula; use as arthropodicide or nematicide | BAYER AKTIENGESELLSCHAFT (DE) | 2003-04-29 | — | — | US | disclosed |
| US-6479489-B1 | AN ARTHROPODICIDAL OR NEMATICIDAL COMPOSITION | BAYER AKTIENGESELLSCHAFT (DE) | 2002-11-12 | — | — | US | disclosed |
| US-5981567-A | ARTHROPODICIDAL OR NEMATICIDAL COMPOSITION | BAYER AKTIENGESELLSCHAFT (DE) | 1999-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040009999-A1 | Substituted spiroheterocyclic 1H-3-aryl-pyrrolidine-2,4-dione derivatives, processes for their preparation, and their use as pesticides | DDT, HPD, CAT | KMT2A 1459/4885P2RX7 924/4885SIGMAR1 2066/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.