SCHEMBL6851371

SCHEMBL6851371

COc1cc2[nH]cc(-c3ccc(N)cc3[N+](=O)[O-])c2cc1OC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
CYP3A4 P08684 3/20 0.41
TSHR P16473 2/20 0.41
RECQL P46063 1/20 0.41
NQO2 P16083 1/20 0.41
MTNR1A P48039 1/20 0.41
MTNR1B P49286 1/20 0.41
TDP1 Q9NUW8 5/20 0.40
KDM4E B2RXH2 2/20 0.40
MAPT P10636 2/20 0.40
BLM P54132 1/20 0.40
ALOX15 P16050 3/20 0.40
HSD17B10 Q99714 2/20 0.38
MAPK1 P28482 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
PDPK1 O15530 1/20 0.37
HTT P42858 1/20 0.37
CHEK1 O14757 1/20 0.37
TUBB4A P04350 3/20 0.36
TUBB P07437 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6851365 0.76 EHMT2 (0.44) ALDH1A1CYP3A4TSHRRECQLTDP1
SCHEMBL6434901 0.73 KDM4E (0.48) ALDH1A1CYP3A4NQO2MTNR1AMTNR1B
SCHEMBL153657 0.73 ALDH1A1 (0.69) ALDH1A1CYP3A4TSHRRECQLTDP1
SCHEMBL2211964 0.72 ALDH1A1 (0.59) ALDH1A1CYP3A4TSHRRECQLTDP1
SCHEMBL29453576 0.72 ALDH1A1 (0.59) ALDH1A1CYP3A4TSHRRECQLTDP1
Hydrochloric Acid SCHEMBL15486437 0.71 ALDH1A1 (0.58) ALDH1A1CYP3A4TSHRRECQLTDP1
SCHEMBL358064 0.69 TDP1 (0.58) ALDH1A1CYP3A4TSHRRECQLTDP1
SCHEMBL31648061 0.68 ALDH1A1 (0.50) ALDH1A1CYP3A4TSHRRECQLTDP1
SCHEMBL15024965 0.67 IMPDH2 (0.49)
SCHEMBL5688128 0.67 ALDH1A1 (0.53) ALDH1A1CYP3A4TSHRRECQLTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6828443-B1 Dyes and colorants HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2004-12-07 US claimed