SCHEMBL15024965

SCHEMBL15024965

O=[N+]([O-])c1cc(Br)ccc1-c1c[nH]c2cc(Br)ccc12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IMPDH2 P12268 1/20 0.49
CYP2A6 P11509 1/20 0.45
ADRA1A P35348 4/20 0.45
ADRA1B P35368 4/20 0.45
S100A4 P26447 1/20 0.44
TRPV1 Q8NER1 1/20 0.44
CLK1 P49759 4/20 0.43
CDK5 Q00535 3/20 0.43
CDK5R1 Q15078 3/20 0.43
CCNB2 O95067 1/20 0.43
CDK1 P06493 1/20 0.43
CCNB1 P14635 1/20 0.43
PRKACA P17612 1/20 0.43
PRKACG P22612 1/20 0.43
PRKACB P22694 1/20 0.43
CSNK1A1 P48729 1/20 0.43
CSNK1D P48730 1/20 0.43
CSNK1E P49674 1/20 0.43
GSK3B P49841 1/20 0.43
CSNK1G2 P78368 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19074303 0.89 TDO2 (0.49) ADRA1AADRA1BS100A4TRPV1CCNB2
SCHEMBL204357 0.80 S100A4 (0.61) S100A4TRPV1
SCHEMBL27007995 0.79 CYP2A6 (0.47) IMPDH2CYP2A6ADRA1AADRA1BS100A4
SCHEMBL28815409 0.74 S100A4 (0.48) CYP2A6S100A4TRPV1PTGES
SCHEMBL24214820 0.73 GPR84 (0.50) CYP2A6S100A4TRPV1CLK1CDK5
SCHEMBL11731287 0.73 GABRA1 (0.54) S100A4TRPV1PTGES
SCHEMBL5443201 0.73 ADRA1A (0.65) IMPDH2CYP2A6ADRA1AADRA1BS100A4
SCHEMBL14906924 0.72 S100A4 (0.56) S100A4TRPV1
SCHEMBL17422753 0.71 IMPDH2 (0.75) IMPDH2CYP2A6ADRA1AADRA1BCLK1
SCHEMBL5321726 0.71 S100A4 (0.54) S100A4TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2617724-B1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL & SUMIKIN CHEM CO (JP) 2017-07-05 EP disclosed
US-8766248-B2 Nitrogen-containing aromatic compound, organic semiconductor material, and organic electronic device NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2014-07-01 US disclosed
US-8766248-B2 Nitrogen-containing aromatic compound, organic semiconductor material, and organic electronic device NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2014-07-01 US disclosed
EP-2617724-A1 NITROGENATED AROMATIC COMPOUND, ORGANIC SEMICONDUCTOR MATERIAL, AND ORGANIC ELECTRONIC DEVICE Nippon Steel & Sumikin Chemical Co., Ltd. (JP) 2013-07-24 EP disclosed
US-20130150576-A1 NITROGEN-CONTAINING AROMATIC COMPOUND, ORGANIC SEMICONDUCTOR MATERIAL, AND ORGANIC ELECTRONIC DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2013-06-13 US disclosed
US-20130150576-A1 NITROGEN-CONTAINING AROMATIC COMPOUND, ORGANIC SEMICONDUCTOR MATERIAL, AND ORGANIC ELECTRONIC DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2013-06-13 US disclosed