Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6846253 | 0.82 | GAA (0.52) | POLBGAAALDH1A1TSHRHSD17B10 | |
| SCHEMBL25369766 | 0.79 | CA1 (0.58) | CA12CA1CA2CA3CA4 | |
| SCHEMBL9577136 | 0.77 | POLB (0.54) | ATMPOLBKMT2AGAAALDH1A1 | |
| SCHEMBL6761822 | 0.76 | PTGES2 (0.49) | KMT2AALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL6849946 | 0.74 | FABP4 (0.55) | MEP1B | |
| SCHEMBL4029646 | 0.73 | WDR5 (0.48) | POLBKMT2AGAAALDH1A1MEP1B | |
| SCHEMBL9577182 | 0.73 | POLB (0.50) | ATMPOLBKMT2AGAAALDH1A1 | |
| SCHEMBL6851801 | 0.72 | CA1 (0.49) | ATMKMT2ACA12CA1CA2 | |
| SCHEMBL6762534 | 0.72 | SLC1A3 (0.48) | ATMPOLBKMT2AGAAHSD17B10 | |
| SCHEMBL31135459 | 0.72 | CA1 (0.46) | ATMKMT2AGAACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774212-B2 | FOR THERAPY OF VIRAL INFECTION OR AS AN ASSAY STANDARD OR REAGENT | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2004-08-10 | — | — | US | disclosed |