SCHEMBL6852237

SCHEMBL6852237

O=Cc1ccc(C(F)(F)c2ccccc2C=O)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.41
LMNA P02545 1/20 0.41
THRB P10828 1/20 0.41
BLM P54132 1/20 0.41
KMT2A Q03164 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
ALDH1A1 P00352 4/20 0.40
CYP2A6 P11509 2/20 0.40
KIF11 P52732 1/20 0.37
NR1H3 Q13133 1/20 0.36
KDM4E B2RXH2 3/20 0.36
TSHR P16473 1/20 0.35
TRIM24 O15164 1/20 0.35
TRIM33 Q9UPN9 1/20 0.35
NFKB1 P19838 1/20 0.35
PPARG P37231 1/20 0.35
HSD17B10 Q99714 1/20 0.33
ALDH5A1 P51649 1/20 0.33
ABAT P80404 1/20 0.33
BACE1 P56817 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17508340 0.87 LMNA (0.46) MEN1LMNATHRBBLMKMT2A
SCHEMBL28275325 0.84 NFKB1 (0.45) MEN1LMNATHRBBLMKMT2A
SCHEMBL17508286 0.79 ALDH1A1 (0.54) KMT2AALDH1A1CYP2A6KIF11TSHR
SCHEMBL26703570 0.79 MEN1 (0.41) MEN1LMNATHRBBLMKMT2A
SCHEMBL6852179 0.78 CYP2A6 (0.46) ALDH1A1CYP2A6KIF11KDM4EHSD17B10
SCHEMBL29417728 0.74 NFKB1 (0.57) MEN1LMNATHRBBLMKMT2A
SCHEMBL67207 0.74 NFKB1 (0.57) MEN1LMNATHRBBLMKMT2A
Ortho-Phthalaldehyde SCHEMBL28300091 0.73 LMNA (0.77) MEN1LMNATHRBBLMKMT2A
SCHEMBL17508341 0.73 LMNA (0.43) MEN1LMNATHRBBLMKMT2A
SCHEMBL28796222 0.71 LMNA (0.50) MEN1LMNATHRBBLMKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6780561-B2 FOR FORMING PROTECTIVE FILM OR AN INSULATING FILM FOR A SEMICONDUCTOR ELEMENT OR A CIRCUIT BOARD SUCH AS A PRINTED BOARD KANSAI PAINT CO., LTD. (JP) 2004-08-24 US disclosed
US-20030143480-A1 For forming protective film or an insulating film for a semiconductor element or a circuit board such as a printed board KANSAI PAINT CO., LTD. (JP) 2003-07-31 US disclosed