Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9067141 | 0.86 | PSIP1 (0.50) | ALDH1A1KMT2APAX8LMNAGAA | |
| SCHEMBL20796169 | 0.83 | ALDH1A1 (0.52) | ALDH1A1THRATHRBKMT2APAX8 | |
| SCHEMBL1018690 | 0.83 | CA12 (0.57) | ALDH1A1THRATHRBKMT2ACYP2C19 | |
| SCHEMBL2027641 | 0.81 | CA2 (0.55) | ALDH1A1THRATHRBKMT2APAX8 | |
| SCHEMBL16225260 | 0.81 | THRA (0.52) | ALDH1A1THRATHRBKMT2APAX8 | |
| SCHEMBL8174782 | 0.80 | PRSS1 (0.50) | ALDH1A1THRATHRBCYP3A4CYP2C9 | |
| SCHEMBL11101781 | 0.77 | KMT2A (0.57) | ALDH1A1KMT2AMEN1GAANPSR1 | |
| SCHEMBL6852673 | 0.76 | ALDH1A1 (0.59) | ALDH1A1KMT2ACYP2C9HTTLMNA | |
| SCHEMBL10619867 | 0.76 | ALDH1A1 (0.47) | ALDH1A1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL2646220 | 0.76 | CA2 (0.53) | ALDH1A1KMT2APAX8CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661289-B1 | Vinyl carboxamide derivatives as insecticides and acaricides | SYNGENTA PARTICIPATIONS AG (CH) | 2004-03-03 | — | — | EP | claimed |