Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.40 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | UGT1A7 | Q9HAW7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6852273 | 0.86 | ALDH1A1 (0.48) | GAALMNAALDH1A1HSD11B1RAB9A | |
| SCHEMBL1403608 | 0.81 | TSHR (0.61) | PSIP1GAATSHRHSD17B10ALDH1A1 | |
| SCHEMBL10451127 | 0.79 | PSIP1 (0.50) | PSIP1GAATSHRHSD17B10ALDH1A1 | |
| SCHEMBL13861088 | 0.79 | MAPT (0.52) | PSIP1GAALMNAALDH1A1HSD11B1 | |
| SCHEMBL4639123 | 0.79 | CA2 (0.61) | PSIP1GAATSHRHSD17B10ALDH1A1 | |
| SCHEMBL10455034 | 0.79 | PSIP1 (0.74) | PSIP1GAALMNAALDH1A1HSD11B1 | |
| SCHEMBL9067806 | 0.78 | ENPP2 (0.54) | — | |
| SCHEMBL8173731 | 0.78 | PRSS1 (0.55) | PSIP1GAALMNAALDH1A1 | |
| SCHEMBL6852673 | 0.77 | ALDH1A1 (0.59) | LMNATSHRALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL1498161 | 0.76 | LMNA (0.52) | LMNATSHRHSD17B10ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726903-A1 | MATRIX METALLOPROTEASE INHIBITORS | SYNTEX INC (US) | 1996-08-21 | — | — | EP | disclosed |
| WO-1995012603-A1 | MATRIX METALLOPROTEASE INHIBITORS________________________________ | SYNTEX (U.S.A.) INC. (US) | 1995-05-11 | — | — | WO | disclosed |