Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SLC9A3 | P48764 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 2/20 | 0.37 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.35 |
| ▸ | BMP1 | P13497 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL328390 | 0.91 | MMP1 (0.43) | BDKRB1BMP1CA9 | |
| SCHEMBL6850664 | 0.90 | DAGLA (0.43) | ALDH1A1SLC9A3ATML3MBTL1LTA4H | |
| SCHEMBL10066710 | 0.85 | LSS (0.41) | ALDH1A1SLC9A3KMT2AMEN1L3MBTL1 | |
| SCHEMBL328414 | 0.85 | DAGLA (0.37) | ALDH1A1KMT2AL3MBTL1DAGLABMP1 | |
| SCHEMBL6852329 | 0.84 | ALDH1A1 (0.41) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL328548 | 0.84 | DAGLA (0.37) | ALDH1A1SLC9A3KMT2AL3MBTL1DAGLA | |
| SCHEMBL328661 | 0.84 | KMT2A (0.38) | ALDH1A1KMT2AL3MBTL1DAGLABMP1 | |
| SCHEMBL6865083 | 0.83 | MMP1 (0.48) | DAGLABMP1CA9 | |
| SCHEMBL6850484 | 0.82 | DAGLA (0.36) | ALDH1A1SLC9A3KMT2AL3MBTL1DAGLA | |
| SCHEMBL328544 | 0.82 | DAGLA (0.35) | ALDH1A1SLC9A3KMT2AL3MBTL1DAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011011181-A1 | PHARMACOLOGICAL CHAPERONES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | AMICUS THERAPEUTICS, INC. (US) | 2011-01-27 | — | — | WO | disclosed |