Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 12/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 6/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | HTT | P42858 | 4/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.57 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.57 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.57 |
| ▸ | MITF | O75030 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21292753 | 0.93 | PHGDH (0.76) | PHGDHMAPTKDM4ETDP1ALDH1A1 | |
| SCHEMBL21292751 | 0.93 | PHGDH (0.76) | PHGDHMAPTKDM4ETDP1ALDH1A1 | |
| SCHEMBL21292769 | 0.90 | PHGDH (0.82) | PHGDHMAPTKDM4ETDP1ALDH1A1 | |
| SCHEMBL21292771 | 0.90 | PHGDH (0.82) | PHGDHMAPTKDM4ETDP1ALDH1A1 | |
| SCHEMBL684813 | 0.87 | DUSP3 (0.76) | PHGDHMAPTKDM4ETDP1ALDH1A1 | |
| SCHEMBL685060 | 0.87 | MAPT (0.72) | MAPTKDM4ETDP1L3MBTL1MEN1 | |
| SCHEMBL684833 | 0.86 | KDM1A (0.73) | PHGDHMAPTKDM4ETDP1ALDH1A1 | |
| SCHEMBL21292819 | 0.85 | PHGDH (0.79) | PHGDHMAPTKDM4ETDP1ALDH1A1 | |
| SCHEMBL16035055 | 0.85 | PHGDH (0.79) | PHGDHMAPTKDM4ETDP1ALDH1A1 | |
| SCHEMBL21292702 | 0.85 | DUSP3 (0.69) | PHGDHMAPTKDM4ETDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120148682-A1 | FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-06-14 | — | — | US | disclosed |
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | SOD1, CYP51A1, SOD3 | PHGDH 1735/4885MAPT 1491/4885KDM4E 1473/4885 |
| US-20120148682-A1 | FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | SOD1, CYP51A1, CYP4Z1 | PHGDH 1393/4885MAPT 921/4885KDM4E 1286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.